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CORRECTION article

Front. Pediatr., 10 November 2021
Sec. Pediatric Gastroenterology, Hepatology and Nutrition
Volume 9 - 2021 | https://doi.org/10.3389/fped.2021.790285

Corrigendum: Age-Related Differences in the Expression of Most Relevant Mediators of SARS-CoV-2 Infection in Human Respiratory and Gastrointestinal Tract

Roberto Berni Canani1,2,3,4* Marika Comegna2,5 Lorella Paparo1,2 Gustavo Cernera2,5 Cristina Bruno1,2 Caterina Strisciuglio6 Immacolata Zollo2,5 Antonietta Gerarda Gravina7 Erasmo Miele1 Elena Cantone8 Nicola Gennarelli9 Rita Nocerino1,2 Laura Carucci1,2 Veronica Giglio1,2 Felice Amato2,5 Giuseppe Castaldo2,5
  • 1Department of Translational Medical Science, University of Naples Federico II, Naples, Italy
  • 2CEINGE-Biotecnologie Avanzate s.c.ar.l., University of Naples Federico II, Naples, Italy
  • 3European Laboratory for the Investigation of Food-Induced Diseases, University of Naples Federico II, Naples, Italy
  • 4Task Force for Microbiome Studies, University of Naples Federico II, Naples, Italy
  • 5Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Naples, Italy
  • 6Department of Woman, Child and General and Specialistic Surgery, University of Campania “Luigi Vanvitelli”, Naples, Italy
  • 7Division of Hepatogastroenterology, Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy
  • 8Department of Neuroscience, Reproductive and Odontostomatological Sciences, Ear, Nose and Throat (ENT) Section, University of Naples Federico II, Naples, Italy
  • 9Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy

A Corrigendum on
Age-Related Differences in the Expression of Most Relevant Mediators of SARS-CoV-2 Infection in Human Respiratory and Gastrointestinal Tract

by Berni Canani, R., Comegna, M., Paparo, L., Cernera, G., Bruno, C., Strisciuglio, C., Zollo, I., Gravina, A. G., Miele, E., Cantone, E., Gennarelli, N., Nocerino, R., Carucci, L., Giglio, V., Amato, F., and Castaldo, G. (2021). Front. Pediatr. 9:697390. doi: 10.3389/fped.2021.697390

In the original article, there was a mistake in the order of Figures 1 and 2 as published. The figures are given in the correct order below.

FIGURE 1
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Figure 1. qPCR analysis of Angiotensin I Converting Enzyme (ACE1), Angiotensin II Converting Enzyme (ACE2), Transmembrane Serine Protease 2 (TMPRSS2), and Neuropilin-1 (NRP1) genes in nasal epithelium from children and adult subjects. Comparative expression of ACE1, ACE2, TMPRSS2, and NRP1 in nasal epithelium of children (n = 15) and adult subjects (n = 15). Data analysis was performed using the comparative threshold cycle (CT) method and expressed as 2∧-delta CT. Gene expression was normalized against the expression of the reference gene hypoxanthine phosphoribosyltransferase 1 (HPRT). Data are expressed as median ± SD, the X in the bars indicates mean values. P-value are reported in the graphs; significant differences are indicated as *p < 0.01; **p < 0.005.

FIGURE 2
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Figure 2. qPCR analysis of Angiotensin I Converting Enzyme (ACE1), Angiotensin II Converting Enzyme (ACE2), Transmembrane Serine Protease 2 (TMPRSS2), and Neuropilin-1 (NRP1) genes in small intestine from children and adult subjects. Comparative expression of ACE1, ACE2, TMPRSS2, and NRP1 in small intestine of children (n = 15) and adult subjects (n = 15). Data analysis was performed using the comparative threshold cycle (CT) method and expressed as 2∧-delta CT. Gene expression was normalized against the expression of the reference gene hypoxanthine phosphoribosyltransferase 1 (HPRT). Data are expressed as median ± SD, the X in the bars indicates mean values. P-value are reported in the graphs; significant differences are indicated as *p < 0.01; **p < 0.005.

The authors apologize for the error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher's Note

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Keywords: COVID-19, angiotensin-converting enzyme 2, transmembrane serine protease-2, neuropilin-1, healthy subjects

Citation: Berni Canani R, Comegna M, Paparo L, Cernera G, Bruno C, Strisciuglio C, Zollo I, Gravina AG, Miele E, Cantone E, Gennarelli N, Nocerino R, Carucci L, Giglio V, Amato F and Castaldo G (2021) Corrigendum: Age-Related Differences in the Expression of Most Relevant Mediators of SARS-CoV-2 Infection in Human Respiratory and Gastrointestinal Tract. Front. Pediatr. 9:790285. doi: 10.3389/fped.2021.790285

Received: 06 October 2021; Accepted: 15 October 2021;
Published: 10 November 2021.

Approved by:

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Copyright © 2021 Berni Canani, Comegna, Paparo, Cernera, Bruno, Strisciuglio, Zollo, Gravina, Miele, Cantone, Gennarelli, Nocerino, Carucci, Giglio, Amato and Castaldo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Roberto Berni Canani, berni@unina.it

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