J Korean Med Sci. 1992 Jun;7(2):162-166. English.
Published online May 26, 2009.
https://doi.org/10.3346/jkms.1992.7.2.162
Published online May 26, 2009.
https://doi.org/10.3346/jkms.1992.7.2.162
Copyright © 1992 The Korean Academy of Medical Sciences
Original Article
Cytogenetic analysis of meningiomas
Jeong Hee Cho,
Gyeong Yeob Gong,
Eun Sil Yu,
Chung Jin Whang,
Kwan Ja Jee
and In Chul Lee
Abstract
Cytogenetic analysis of 4 cases of meningiomas from 3 male and 1 female patients is reported. One of male patients suffered from neurofibromatosis type 2. Histologically, the meningiomas were meningotheliomatous (1), transitional (2), and psammomatous (1). Chromosomal abnormalities were found in all cases with a karyotype 45,XY,-22, 45,XY,-16, 45,XX,-2, and 45,XY,t (15p;22q), respectively. Monosomy of chromosome 22 was detected only in the patient with neurofibromatosis type 2. These cytogenetic analysis demonstrates that variable clonal karyotype aberrations exist in meningiomas.
Keywords
Meningioma; chromosomal analysis; neurofibromatosis-2
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MeSH Terms
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