ABSTRACT

Key physiological principles See also key physiological principles in Exercise Training 1. • Individuals with lung disease are often extremely sedentary due to the fear of dyspnea. • Even mild lung disease may result in muscle weakness secondary to deconditioning,

hypoxia, malnutrition or sepsis (Morgan 1999). Lower limb muscles are often atrophied, and blood lactate levels elevated at very low work rates (Casaburi 1992).