Sharifi Nasab M, Yazdimoghaddam H, Mohaddess S T, Rakhshani M H. Correlations of Diabetes and the Risk Factors with the Survival of Breast Cancer Patients. ijbd 2022; 14 (4) :31-44
URL:
http://ijbd.ir/article-1-914-en.html
1- Faculty of Nursing and Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran & Department of Nursing, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
2- Department of Operating Room, Iranian Research Center on Healthy Aging, Faculty of Paramedics, Sabzevar University of Medical Sciences, Sabzevar, Iran , ha_yazdimoghaddam@yahoo.com
3- Department of Hematology & Medical Oncology, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4- Department of Biostatistics and epidemiology, Iranian Research Center on Health Aging, School of Public Health, Sabzevar University of Medical Sciences, Sabzevar, Iran
Abstract: (3389 Views)
Introduction: Diabetes is associated with an increased risk of cancer. Because of the metastatic nature of cancer, the survival of women with breast cancer is decreasing despite receiving various treatments such as chemotherapy, radiotherapy, etc. The aim of this study was to investigate the relationship between diabetes and the risk factors related to the survival of breast cancer patients.
Methods: This was a descriptive-analytical study. Patients were selected via systematic random sampling and then divided into diabetic and nondiabetic groups. Then the 5-year survival rate of patients was were compared.
Results: The mean and median for survival were 9.95 and 13.00 years. The risk of death in breast cancer patients positive for estrogen receptor was significantly reduced compared with patients negative for estrogen receptor (HR, 0.314; 95% CI, 0.109–0.907; P = 0.03).
Conclusion: The results of the study indicate that the survival of breast cancer patients in diabetics is not significantly different from non-diabeticsUse of metformin and estrogen receptor positivity is associated with higher 5-year survival rates in women with breast cancer. Therefore, cancer screening programs in high-risk groups, especially in diabetic patients, and hyperglycemic control may affect survival time.
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Conclusion: The results of the study indicate that the survival of breast cancer patients in diabetics is not significantly different from non-diabeticsUse of metformin and estrogen receptor positivity is associated with higher 5-year survival rates in women with breast cancer. Therefore, cancer screening programs in high-risk groups, especially in diabetic patients, and hyperglycemic control may affect survival time.
Type of Study:
Research |
Received: 2021/09/10 | Accepted: 2021/12/22 | Published: 2022/02/20