Towards a new concept for high sensitivity Compton scatter emission imaging

M. K. Nguyen; C. Driol; T. T. Truong; H. Zaidi

doi:10.2971/jeos.2008.08010

Journal of the European Optical Society - Rapid publications, Vol 3 (2008)

Towards a new concept for high sensitivity Compton scatter emission imaging

M. K. Nguyen, C. Driol, T. T. Truong, H. Zaidi

Abstract

A new efficient scheme for imaging gamma-emitting objects is advocated in this work. It is elaborated on the recent idea of collecting data, using a detector equipped with a parallel-hole collimator, from Compton scattered photons to reconstruct an object in three-dimensions. This paper examines a working mode without collimation, which should increase its sensitivity and field of view. To simplify the otherwise complex mathematical formulation, we choose to discuss the image formation process in two-dimensions, which can be implemented with a slit collimator. Comparison with the standard collimated case, via the analysis of the shapes of the respective point spread functions (PSF), shows marked improvements and numerical simulation results, obtained using a brain phantom, support the viability and attractiveness of this new imaging modality.

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References

H. Zaidi and K. F. Koral, "Scatter modelling and compensation in emission tomography" Eur. J. Nucl. Med. Mol. I. 31, 761-782 (2004).

M.K. Nguyen and T.T. Truong, "On an integral transform and its inverse in nuclear imaging" Inverse Probl. 18, 265-277 (2002).

M.K. Nguyen and T.T. Truong and H.D. Bui and J.L. Delarbre, "A novel inverse problem in gamma-ray emission imaging" Inverse Probl. Sci. En. 12, 225-246 (2004).

M.K. Nguyen and T. T. Truong and J. L. Delarbre and C. Roux and H. Zaidi, "Novel approach to stationary transmission scanning using Compton scattered radiation" Phys. Med. Biol. 52, 4615-4632, (2007).

T. T. Truong and M. K. Nguyen and H. Zaidi, "The mathematical foundations of 3D Compton scatter emission imaging" International Journal of Biomedical Imaging doi: 10.1155/2007/92780 (2007).

H. Zaidi, "Recent developments and future trends in nuclear medicine instrumentation" Med. Phys. 16, 5-17 (2006).

R. L. Clarke and E. N. C. Milne and G. Van Dyk, "The use of Compton scattered gamma rays for tomography" Invest. Radiol. 11, 225-235 (1976).

B. L. Evans and J. B. Martin and L. W. Burggaf and M. C. Roggemann. "Nondestructive Inspection Using Compton Scatter Tomography" IEEE T. Nucl. Sci. 45, no.3 (1998).

E.M.A. Hussein, "Compton scatter imaging systems" in Bioinstrumentation: Research, Developments and Applications, Donald L. Wise, ed., chapter 35, 1053-1086 (Butterworths 1990).

P.C. Johns and R.J. Leclair and M.P. Wismayer, "Medical X-ray Imaging with Scattered Photons" in Opto-Canada: SPIE Regional Meeting in Optoelectronics, Photonics and Imaging, SPIE TD 01, 355-357 (Ottawa, Canada 2002).

S. J. Norton, "Compton scattering tomography" J. Appl. Phys. 76, 2007-2015 (1994).

M. Singh, "An electronically collimated gamma camera for single photon emission computed tomography" Med. Phys. 10, 421-427 (1983).

S. Chelikani and J Gore and G Zubal, "Optimizing Compton camera geometries" Phys. Med. Biol. 49, 1387-1408 (2004).

L. Mihailescu and K. M. Vetter and M. T. Burks and E. L. Hull and W. W. Craig, "SPEIR: A Ge Compton camera" Nucl. Instrum. Meth. A 570, 89-100 (2007).

G. L. Zeng and D. Gagnon, "CdZnTe strip detector SPECT imaging with a slit collimator" Phys. Med. Biol. 49, 2257-2271 (2004).

H. Zaidi, "Relevance of accurate Monte Carlo modeling in nuclear medical imaging" Med. Phys. 26, 574-608 (1999).

C. Driol and M.K. Nguyen and T.T. Truong, "Modelling and simulation results on high sensitivity scattered g-ray imaging" in Proc. 6th EUROSIM Congress on Modelling and Simulation (Ljubljana- Slovenia 2007).

V. V. Selivanov and D. Lapointe and M. Bentourkia and R. Lecomte, "Cross validation stopping rule for ML-EM reconstruction of dynamic PET series effect" IEEE T. Nucl. Sci. 48, 883-889 (2001).