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Abstract

We describe detection in the United Kingdom (UK) of the drug-resistant FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain.

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/content/10.2807/1560-7917.ES.2019.24.10.1900147
2019-03-07
2024-04-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2019.24.10.1900147
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Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=David+W+Eyre&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Eyre David W</a>, <a href="/search?value1=Katy+Town&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Town Katy</a>, <a href="/search?value1=Teresa+Street&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Street Teresa</a>, <a href="/search?value1=Leanne+Barker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barker Leanne</a>, <a href="/search?value1=Nicholas+Sanderson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sanderson Nicholas</a>, <a href="/search?value1=Michelle+J+Cole&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cole Michelle J</a>, <a href="/search?value1=Hamish+Mohammed&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mohammed Hamish</a>, <a href="/search?value1=Rachel+Pitt&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pitt Rachel</a>, <a href="/search?value1=Maya+Gobin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gobin Maya</a>, <a href="/search?value1=Charles+Irish&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Irish Charles</a>, <a href="/search?value1=Daniel+Gardiner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gardiner Daniel</a>, <a href="/search?value1=James+Sedgwick&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sedgwick James</a>, <a href="/search?value1=Charles+Beck&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Beck Charles</a>, <a href="/search?value1=John+Saunders&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Saunders John</a>, <a href="/search?value1=Deborah+Turbitt&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Turbitt Deborah</a>, <a href="/search?value1=Clare+Cook&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cook Clare</a>, <a href="/search?value1=Nick+Phin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Phin Nick</a>, <a href="/search?value1=Bavithra+Nathan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nathan Bavithra</a>, <a href="/search?value1=Paddy+Horner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Horner Paddy</a>, <a href="/search?value1=Helen+Fifer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fifer Helen</a></span>. Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018. <a href="/content/ecdc">Euro Surveill.</a> 2019;24(10):pii=1900147. <a href="https://doi.org/10.2807/1560-7917.ES.2019.24.10.1900147" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2019.24.10.1900147</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 22 Feb 2019;&nbsp;&nbsp; <span class="generated">Accepted</span>: 06 Mar 2019 </span> </p>
/content/10.2807/1560-7917.ES.2019.24.10.1900147
/content/10.2807/1560-7917.ES.2019.24.10.1900147
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