Welcome to Francis Academic Press

International Journal of Frontiers in Medicine, 2022, 4(7); doi: 10.25236/IJFM.2022.040702.

Ultrasonographic Characteristics Analysis of Papillary Thyroid Carcinoma with Hashimoto's Thyroiditis in Different Functional States

Author(s)

Yafei Guo1, Wenjing Yang2, Yuhang Tan1, Qili Zhang1, Ruijun Guo1

Corresponding Author:
Ruijun Guo
Affiliation(s)

1Department of Ultrasound, Beijing Chaoyang Hospital of Capital Medical University, Beijing, China

2Department of Thyroid and Neck Surgery, Beijing Chaoyang Hospital of Capital Medical University, Beijing, China

Abstract

The ultrasonographic characteristics of thyroid papillary carcinoma with and without hashimoto's thyroiditis were compared and analyzed to explore the effect of hashimoto's thyroiditis on ultrasonographic characteristics of thyroid papillary carcinoma, in order to improve the accuracy of ultrasonic diagnosis. Method 91 patients with thyroid papillary carcinoma confirmed by surgical resection and pathological biopsy in Beijing Chaoyang Hospital, Capital Medical University from September 2018 to November 2021 were retrospectively analyzed. Result The maximum diameter, blood flow grade and lymph node metastasis rate of papillary thyroid carcinoma in hashimoto's thyroiditis group were significantly higher than those in non-hashimoto thyroiditis group (P < 0.05). There were significant differences in the growth pattern, hardness and Ratio of papillary thyroid carcinoma among the three subgroups (P < 0.05). Conclusion Under different functional states, thyroid papillary carcinoma combined with hashimoto's thyroiditis showed differences in the growth pattern, hardness, blood grade and other sonographic characteristics.

Keywords

Hashimoto's thyroiditis; Papillary thyroid carcinoma; Shear wave elastography; Superb Micro-Vascular Imaging; Ultrasonography

Cite This Paper

Yafei Guo, Wenjing Yang, Yuhang Tan, Qili Zhang, Ruijun Guo. Ultrasonographic Characteristics Analysis of Papillary Thyroid Carcinoma with Hashimoto's Thyroiditis in Different Functional States. International Journal of Frontiers in Medicine (2022), Vol. 4, Issue 7: 7-12. https://doi.org/10.25236/IJFM.2022.040702.

References

[1] Ralli M, Angeletti D, Fiore M, et al. Hashimoto's thyroiditis: Anupdate on pathogenic mechanisms, diagnostic protocols, therapeutic strategies, and potential malignant transformation. Autoimmun Rev,2020,19(10):102-106.DOI: 10.1016/j.autrev.2020.102649. 

[2] Paknys G, Kondrotas AJ, Kevelaitis E. Risk factors and pathogenesis of Hashimoto's thyroiditis.Medicina (Kaunas),2009,45(7):574-583. 

[3] Chahardoli R, Saboor-Yaraghi AA, Amouzegar A,et al. Can Supplementation with Vitamin D Modify Thyroid Autoantibodies (Anti-TPO Ab, Anti-Tg Ab) and Thyroid Profile (T3, T4, TSH) in Hashimoto's Thyroiditis? A Double Blind, Randomized Clinical Trial. Horm Metab Res,2019,51(5):296-301. DOI:10.1055/a-0856-1044.

[4] Chen xun,Hao mengyuan, Li ronghai, etal. Significance of TPOAb and TgAb detection in Hashimoto's thyroiditis. International Journal of Laboratory Medicine ,2021,14(21):1673. DOI:10. 3969/j.issn.1673-4130.2021.21.014.

[5] Nath MC, Erickson LA. Aggressive Variants of Papillary Thyroid Carcinoma: Hobnail, Tall Cell, Columnar, and Solid. Adv Anat Pathol, 2018,25(3):172-179. DOI:10.1097/PAP.0000000000000184. 

[6] Uhliarova B, Hajtman A. Hashimoto's thyroiditis - an independent risk factor for papillary carcinoma. Braz J Otorhinolaryngol, 2018,84(6):729-735.DOI: 10.1016/j.bjorl.2017.08.012. 

[7] Lee JH, Kim Y, Choi JW, Kim YS. The association between papillarythyroid carcinoma and histologically proven Hashimoto's thyroiditis: a meta-analysis. Eur J Endocrinol. 2013,168(3):343-349. DOI: 10.1530/EJE-12-0903.

[8] Zhang D, Mu J, Mao YR, Wang Y, Xin XJ. Application value of superb microvascular imaging for diagnosis of different size renal solid tumors. Zhonghua Zhong Liu Za Zhi, 2021,43(11):1215-1221. DOI: 10.3760/cma.j.cn112152-20191220-00832.

[9] Hanege FM, Tuysuz O, Celik S, Sakallıoglu O, Arslan Solmaz O. Hashimoto's thyroiditis inpapillary thyroid carcinoma: a 22-year study. Acta Otorhinolaryngol Ital, 2021,41(2):142-145. DOI:10.14639/0392-100X-N1081. 

[10] Jankovic B, Le KT, Hershman JM. Clinical Review: Hashimoto's thyroiditis and papillary thyroid carcinoma: is there a correlation? J Clin Endocrinol Metab, 2013,98(2):474-482. DOI: 10.1210/jc.2012-2978.

[11] Noureldine SI, Tufano RP. Association of Hashimoto's thyroiditis and thyroid cancer. Curr Opin Oncol,2015,27(1):21-25.DOI:10.1097/CCO.0000000000000150. 

[12] Lv Y, He X, Yang F, Guo L, Qi M, Zhang J, Wang H. Correlation of conventional ultrasound features and related factors with BRAFV600E gene mutation in papillary thyroid carcinoma. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2021, 35 (10): 925-929.DOI: 10.13201/j.issn.2096-7993.2021.10.013.

[13] Lai X, Xia Y, Zhang B, Li J, Jiang Y. A meta-analysis of Hashimoto's thyroiditis and papillary thyroid carcinoma risk. Oncotarget,2017,8(37):62414-62424.DOI: 10.18632/oncotarget.18620.

[14] Ma Y, Li G, Li J, Ren WD. The Diagnostic Value of Superb Microvascular Imaging (SMI) in Detecting Blood Flow Signals of Breast Lesions: A Preliminary Study Comparing SMI to Color Doppler Flow Imaging. Medicine (Baltimore), 2015, 94 (36):e1502. DOI:10.1097/MD. 0000000000001502.

[15] Zhu YC, Zhang Y, Deng SH, Jiang Q. A Prospective Study to Compare Superb Microvascular Imaging with Grayscale Ultrasound and Color Doppler Flow Imaging of Vascular Distribution and Morphology in Thyroid Nodules. Med Sci Monit,2018,24:9223-9231.DOI: 10.12659/MSM.911695. 

[16] Chao G, Zhu Y, Fang L. Correlation Between Hashimoto's Thyroiditis-Related Thyroid Hormone Levels and 25-Hydroxyvitamin D. Front Endocrinol (Lausanne). 2020,14;11-14. DOI: 10.3389/fendo.2020.00004. 

[17] Farhangi MA, Dehghan P, Tajmiri S, Abbasi MM. The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin-1 and anthropometric features in patients with Hashimoto's thyroiditis: a randomized controlled trial. BMC Complement Altern Med, 2016 Nov 16;16(1):471. DOI:10.1186/s12906-016-1432-2. 

[18] Li T, Li H, Xue J, Miao J, Kang C. Shear wave elastography combined with gray-scale ultrasound for predicting central lymph node metastasis of papillary thyroid carcinoma. Surg Oncol,2021,36:1-6.DOI:10.1016/j.suronc.2020.11.004.

[19] Liu Xiaoli, Chen Xia, Yu Shaomei, et al. Clinical value of shear wave elastography in the detection of thyroid nodules Young’s modulus value and Ratio value in identifying benign and malignance. China Modern Medicine,2015,22(36):49-52.

[20] Lian Yi, Huang Ying, IAN Yi. Correlation between Shear Wave Elastic Modulus and Pathological Basis of Breast Lesions. China Medical Devices,2021, 36(1):83-86.DOI:10.3969/j.issn.1674-1633.