초록

이 연구는 트레드밀 운동과 밝은 빛이 흰쥐 뇌의 세로토닌 발현에 미치는 영향을 조사하는데 그 목적이 있다. 수컷 흰쥐는 임의로 아홉 마리씩 네 집단(통제집단, 운동집단, 빛집단, 운동+빛집단)으로 분류하였다. 운동집단은 일주일에 5일, 하루에 30분씩 운동하였고, 빛집단은 일주일에 5일 하루에 30분씩 10,000 lux의 빛을 쬐었으며 운동+빛집단은 운동과 빛을 위 두 방식대로 복합처치 되었다. 실험기간은 4주간이며 통제집단은 아무런 실험처치 없이 사육되었다. 우리는 통제집단에 비해 나머지 집단에서 회봉선핵과 중뇌에서 세로토닌의 발현이 유의미하게 증가된 것을 알았다. 흥미로운 것은 세로토닌의 발현이 면역조직화학법에서 운동집단과 빛집단에 비해 운동+빛집단에서 유의미하게 증가된 것이고, 면역얼룩법에서도 유의미한 증가는 아니지만 증가의 양상을 보였다는 것이다. 결과적으로 트레드밀 운동과 밝은 빛은 뇌의 세로토닌 발현에 긍정적인 효과가 있음을 알 수 있었다. 그러므로 우리는 성장기에 밝은 빛을 쬐면서 운동을 하는 것은 뇌 활동에 도움이 될 것이라 제안한다.

키워드

운동, 밝은 빛, 세로토닌, 뇌

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