Kidney Res Clin Pract > Volume 38(3); 2019 > Article |
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Authors’ contributions
Il-Soo Ha, Hae Il Cheong, and Hee Gyung Kang participated in the conceptualization. Ye Kyung Kim, and Myung Hyun Cho participated in the data curation. Ye Kyung Kim participated in the formal analysis and original draft. Myung Hyun Cho, Hye Sun Hyun, and Eujin Park participated in the investigation. Hee Gyung Kang participated in the methodology. Myung Hyun Cho, and Hee Gyung Kang participated in the review and editing. All authors read and approved the final manuscript.
Case No. | 1a | 2 | 3 | 4 | 5 | 6a | 7 | 8a | 9 | Average |
---|---|---|---|---|---|---|---|---|---|---|
Fever patterns | Mono | Mono | Bi | Mono | Mono | Tri | Mono | Bi | Mono | |
Symptoms onset day from fever (d) | ||||||||||
Abdominal pain | 3 | 3 | – | 2 | 5 | – | 0 | 0 | 8 | 3.0 |
Diarrhea or loose stool | 3 | – | 0 | 0 | 5 | 7 | – | 6 | 8 | 4.1 |
Rash | – | 3 | – | 7 | – | 0 | – | 0 | – | 2.5 |
Oliguria | 4 | 8 | 7 | 3 | 6 | 8 | 5 | 7 | 10 | 6.4 |
Symptom duration (d) | ||||||||||
Fever | 8 | 11 | 18 | 6 | 12 | 20 | 11 | 14 | 17 | 13.0 |
Abdominal pain | 7 | 9 | – | 8 | 10 | – | 9 | 14 | 8 | 9.3 |
Diarrhea or loose stool | 7 | – | 13 | 16 | 11 | 8 | – | 3 | 4 | 8.9 |
Rash | – | 5 | – | 2 | – | 2 | – | 3 | – | 3.0 |
Oliguria | 5 | 4 | 17 | 6 | 5 | 4 | 4 | 7 | 5 | 6.3 |
Urine output (mL/kg/hour)b | < 0.5 | < 0.5 | < 0.5 | 0.8 | 0.8 | < 0.5 | 1.5 | < 0.5 | N/A | |
Hypertension | − | + (> 90p) | + (> 90p) | N/A | − | + (> 95p) | N/A | N/A | + | |
Generalized edema | + | + | + | + | + | + | + | + | − | |
Mucocutaneous manifestations | ||||||||||
Desquamation | − | − | − | − | + | + | − | + | − | |
Strawberry tongue | − | − | − | − | − | − | − | − | − | |
Conjunctival injection | − | − | − | − | − | − | − | − | − | |
Erythema nodosum | − | − | − | − | − | − | − | − | − |
Case No. | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | n (%) or n/total n (%) |
---|---|---|---|---|---|---|---|---|---|---|
Total blood test | ||||||||||
Minimum hemoglobin (g/dL) | 10.0 | 9.9 | 8.0 | 9.1 | 9.5 | 9.7 | 9.4 | 7.5 | 11.1 | 9.4a |
Maximum WBC count (/mm3) | 27,510 | 24,340 | 43,600 | 13,540 | 10,800 | 11,460 | 16,180 | 14,640 | 17,570 | 19,960a |
Maximum platelet count (×1,000/mm3) | 527 | 587 | 667 | 267 | 335 | 755 | 440 | 689 | 464 | 526a |
CRP (mg/dL) | 23.39 | 22.63 | 27.78 | 21.5 | 18.98 | 23.14 | 26.18 | 33.5 | 19.3 | |
Maximum BUN (mg/dL) | 84 | 65 | 89 | 69 | 39 | 56 | 40 | 57 | 46 | |
Maximum Cr (mg/dL) | 9.22 | 8.61 | 6.27 | 4.77 | 4.07 | 7.00 | 3.03 | 3.99 | 4.5 | |
FENa (%) | 2.4 | 1.2 | N/A | 13.4 | 3.5 | 12.5 | 1.4 | 2.8 | 1.3 | |
Complement levels, C3/C4 | wnl | wnl | wnl | wnl | N/A | N/A | N/A | wnl | wnl | 0 |
IgG/IgA/IgM | wnl | wnl | wnl | wnl | N/A | N/A | N/A | wnl | wnl | 0 |
FANA | + | + | + | − | N/A | N/A | N/A | +/− | +/− | 3/6 (50.0) |
Widal test O | − | − | − | − | − | + | − | − | N/A | 1/8 (12.5) |
Widal test H | − | − | − | − | − | − | − | − | N/A | 0 |
ANCA | − | − | − | − | N/A | N/A | N/A | N/A | − | 0 |
Urinary analysis | ||||||||||
Pyuria (WBC > 5/HPF) | + | + | + | − | + | − | + | + | + | 7 (77.8) |
Proteinuria | + | + | + | + | + | + | + | + | + | 9 (100) |
Glucosuria | + | + | + | + | + | + | + | + | − | 8 (88.9) |
Hematuria (RBC > 5/HPF) | + | − | + | − | − | + | − | + | − | 4 (44.4) |
Protein/Creatinine ratio | 2.51 | 1.23 | 4.65 | 4.64 | 1.91 | 1.84 | 2.04 | 4.8 | N/A | |
Stool analysis | ||||||||||
Yersinia culture | − | − | − | − | − | − | + | − | N/A | 1/8 (12.5) |
Kidney SONO | + | − | + | + | + | + | − | + | + | 7 (77.8) |
Increased renal parenchymal echogenicity | + | N/A | + | + | + | + | N/A | + | + | 7/7 (100) |
Renal parenchymal swelling or | − | N/A | + | + | + | + | N/A | + | + | 6/7 (85.7) |
renomegaly | ||||||||||
Abdomen SONO | + | + | − | − | − | + | + | + | + | 6 (66.7) |
Abdomen CT | − | − | + | − | − | + | + | − | − | 3 (33.3) |
Enlarged or increased echogenicity of mesenteric LN | + | + | + | N/A | N/A | − | − | + | − | 4/7 (57.1) |
Ileum wall thickening | − | + | + | N/A | N/A | + | + | + | − | 5/7 (71.4) |
GB wall edema | − | + | + | + | − | − | − | + | − | 4 (44.4) |
Ascites | + | + | + | − | + | − | − | + | + | 6 (66.7) |
Pleural effusion | + | − | + | − | − | − | − | − | − | 2 (22.2) |
Echocardiography | + | + | + | + | + | + | + | + | − | 8 (88.9) |
Coronary artery dilatation | − | − | − | − | − | − | − | − | N/A | 0 |
ANCA, anti-neutrophil cytoplasmic antibody; BUN, blood urea nitrogen; Cr, creatinine; CRP, C-reactive protein; CT, computed tomography; FANA, fluorescent antinuclear antibody; FENa, fractional excretion of sodium; GB, gall bladder; HPF, high power field; Ig, immunoglobulin; LN, lymph node; N/A, not applicable; RBC, red blood cell; SONO, sonography; WBC, white blood cell; wnl, within normal limit; −, unfulfilled or negative finding.