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ORIGINAL ARTICLE
Minerva Pediatrics 2023 February;75(1):26-31
DOI: 10.23736/S2724-5276.16.04418-X
Copyright © 2016 EDIZIONI MINERVA MEDICA
language: English
Epidemiological and clinical characteristics of human rhinovirus caused bronchiolitis in children in Southeast China
Yuqing WANG 1, Wei JI 1 ✉, Chuangli HAO 1, Yongdong YAN 1, Wujun JIANG 1, Xuejun SHAO 2, Jun XU 2
1 Department of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, China; 2 Department of Clinical Laboratory, Children’s Hospital of Soochow University, Suzhou, China
BACKGROUND: Human rhinovirus (hRV) is a critical viral pathogen implicated in bronchiolitis in children. However, there is no study on hRV bronchiolitis in children from Southeast China. The aim of this study was to determine the incidence and clinical features of hRV bronchiolitis in Southeast China.
METHODS: The study was carried out in Children’s Hospital of Soochow University on children admitted with the diagnosis of bronchiolitis from January 2013 to December 2014. hRV was tested using reverse-transcription polymerase chain reaction.
RESULTS: hRV was identified in 140 of 797 specimens (17.6%). hRV was detected with a highest rate in June and August. The hRV positive rate in patients younger than 6 months of age was significantly lower than that in other age groups (P<0.01). The most common radiological finding was hyperinflation (51.4%). Patients with hRV infection were older and more likely to have eczema than those with RSV.
CONCLUSIONS: The hRV was an important viral pathogen associated with bronchiolitis in children with an epidemic peak in summer. Most of patients were between 6 to 24 months and with a high presence of eczema.
KEY WORDS: Bronchiolitis; Rhinovirus; Infant