REVIEW  INTERVENTIONAL NUCLEAR MEDICINE Free access

The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2021 March;65(1):4-19

DOI: 10.23736/S1824-4785.21.03286-6

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Interventional nuclear medicine: a focus on radioguided intervention and surgery

Daphne D. RIETBERGEN ^{1, 2}, Matthias N. VAN OOSTEROM ^{2, 3}, Gijs H. KLEINJAN ⁴, Oscar R. BROUWER ^{2, 3}, Renato A. VALDES-OLMOS ¹, Fijs W. VAN LEEUWEN ^{2, 3}, Tessa BUCKLE ^{2, 3} ✉

¹ Section of Nuclear Medicine, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands; ² Department of Radiology, Interventional Molecular Imaging Laboratory, Leiden University Medical Center, Leiden, the Netherlands; ³ Department of Urology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands; ⁴ Department of Urology, Leiden University Medical Center, Leiden, the Netherlands

Within interventional nuclear medicine (iNM) a prominent role is allocated for the sub-discipline of radioguided surgery. Unique for this discipline is the fact that an increasing number of clinical indications (e.g. lymphatic mapping, local tumor demarcation and/or tumor receptor targeted applications) have been adopted into routine care. The clinical integration is further strengthened by technical innovations in chemistry and engineering that enhance the translational potential of radioguided procedures in iNM. Together, these features not only ensure ongoing expansion of iNM but also warrant a lasting clinical impact for the sub-discipline of radioguided surgery.

KEY WORDS: General surgery; Nuclear medicine; Molecular imaging