SPECIAL ARTICLE  LYMPHOLOGY Free access

International Angiology 2020 October;39(5):422-32

DOI: 10.23736/S0392-9590.20.04333-3

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Lymphology and translational medicine

Attilio CAVEZZI ✉, Roberto COLUCCI, Stefania PACCASASSI, Martina PIERGENTILI

Eurocenter Venalinfa, San Benedetto del Tronto, Ascoli Piceno, Italy

Lymphology is evolving in search of a better management of lymphedema patients, both as to the diagnostic pathway and as to the therapeutic options. Similarly, lymphatic system is involved in a wide spectrum of pathophysiologic processes of most chronic degenerative diseases. Translational medicine integrates the interdisciplinary scientific knowledge to improve diagnostic and therapeutic options in the biomedical field. Inflammation and lymphatic function are regarded as the connecting biochemical factors in most diseases. This review focuses on the scientific publications regarding lymphatic system in connection to psycho-neuroendocrine immunology, hormesis, epigenetics and more generally nutrition and lifestyle. The interaction between lymphology and translational medicine may play a relevant role to improve management of lymphedema on the one hand, and of chronic degenerative diseases on the other.

KEY WORDS: Lymphology; Lymphedema; Translational medicine; Immunology; Hormesis