doiSerbia

Morphological characteristics of the myocardial bridges in the level of the anterior interventricular branch of a human fetal heart

Čukuranović Ognjen (Faculty of Medicine, Niš)
Mandarić Vladimir (Military Medical Academy, Clinic for Cardiosurgery, Belgrade)
Pantović Vukica (Public Health Institute, Niš)
Mihailović Dragan (Faculty of Medicine, Department of Pathology, Niš)
Jovanović Ivan (Faculty of Medicine, Department of Anatomy, Niš)
Veljković-Čukuranović Aleksandra (Faculty of Medicine, Niš)
Čukuranović-Kokoris Jovana (Faculty of Medicine, Department of Anatomy, Niš)
Vasović Ljiljana (Faculty of Medicine, Department of Anatomy, Niš)

Background/Aim. Myocardial bridges (MB) are narrower or wider fascicles of the atrial or ventricular muscle fibres which form a “bridge” either across the main trunks of coronary arteries or their major subepicardial branches. The aim of this research was to determine and present the exact frequency, morphological, morphometric and histological characteristics of the MB in the level of anterior interventricular branch (AIB) in human fetal hearts. Methods. The study was performed on 63 human fetal hearts. Images of the analyzed hearts were captured with a digital camera and afterwards morphometrically evaluated with ImageJ. Characteristic cases of the MB were dissected, sampled and further routinely processed for the subsequent histological analysis. Finally, the obtained morphometric data were statistically analyzed. Results. The presence of the MB on the AIB was proven histologically and under the magnifying glass. Myocardial bridges were found in 53.97% of the hearts. The percentage of the hearts with only one MB detected on AIB 88.24% was significantly higher than the percentage of the hearts with two MBs on the AIB (11.76%) (p < 0.001). Conclusion. We suggest that the MBs are just one anatomical variation of the fetal period as well as of adulthood.

Keywords: fetus, heart, coronary vessels, abnormalities, myocardial bridging

Projects of the Serbian Ministry of Education, Science and Technological Development, Grant no. 175092 and Grnat no. III 41017