Vojnosanitetski pregled 2016 Volume 73, Issue 6, Pages: 599-602
https://doi.org/10.2298/VSP140602051E
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PET/CT fusion in radiotherapy planning for lung cancer - case reports
Erak Marko Đ. (Faculty of Medicine, Novi Sad + Oncology Institute of Vojvodina, Sremska Kamenica)
Mitrić Milana (Oncology Institute of Vojvodina, Sremska Kamenica)
Đuran Branislav (Faculty of Medicine, Novi Sad + Oncology Institute of Vojvodina, Sremska Kamenica)
Tešanović Dušanka (Oncology Institute of Vojvodina, Sremska Kamenica)
Vasiljev Sanja (Oncology Institute of Vojvodina, Sremska Kamenica)
Introduction. Application of imaging methods, namely computed tomography
(CT), magnetic resonance imaging (MRI) and in recent years positron emission
tomography-computed tomography (PET/CT), and the progress of computer
technology have allowed the construction of effective computerized systems
for treatment planning (TPS) and introducing the concept of virtual
simulation in 3D conformal radiotherapy planning. Case report. We hereby
presented two patients with the diagnosis of non-small cell lung cancer who
did PET/CT examination. Both patients had surgery earlier and local recidives
are diagnosed with PET/CT. PET/CT of the first patient described the focus of
intense fluorodeoxyglucose (FDG) accumulation 2.99 × 2.9 × 2.1cm in diameter
in the projection of soft-tissue volume in the left corner, at operating
clips height, corresponding to metabolically active recurrence of the tumor.
Mediastinum and right lung parenchyma were without focal accumulation of FDG.
Control PET/CT after 3 months was without detectable focus of intense
pathological FDG accumulation - good therapeutic response, (metabolic disease
remission). On the other hand, in the second case PET/CT showed a focus of
intense FDG accumulation screening in the scar tissue of the apical part of
the right lung, 20 × 16 mm, corresponding to metabolically active tumor
recurrence. In the lung parenchyma on the left and in the mediastinum no
visible focus of intense FDG accumulation was descrbed. Radiography included
using 3D conformal radiotherapy with fusion PET/CT scan and CT simulations.
Conclusion. PET/CT provides important information for planning conformal
radiotherapy, especially in dose escalation, sparing of organ at risk and
better locoregional control of the disease.
Keywords: carcinoma, non-small-cell lung, radiotherapy, conformal, positron-emission tomography