Vojnosanitetski pregled 2013 Volume 70, Issue 10, Pages: 972-975
https://doi.org/10.2298/VSP1310972B
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Extramedullary plasmacytoma of the tongue base: A rare presentation of head and neck plasmacytoma
Bila Jelena (Clinical Center of Serbia, Clinic for Hematology, Belgrade + Faculty of Medicine, Belgrade)
Anđelić Boško (Clinical Center of Serbia, Clinic for Hematology, Belgrade)
Bodrožić Jelena (Clinical Center of Serbia, Clinic for Hematology, Belgrade)
Jaković Ljubomir (Clinical Center of Serbia, Clinic for Hematology, Belgrade)
Peruničić-Jovanović Maja (Clinical Center of Serbia, Clinic for Hematology, Belgrade)
Vidović Ana (Clinical Center of Serbia, Clinic for Hematology, Belgrade + Faculty of Medicine, Belgrade)
Todorović Milena (Clinical Center of Serbia, Clinic for Hematology, Belgrade + Faculty of Medicine, Belgrade)
Mihaljević Biljana (Clinical Center of Serbia, Clinic for Hematology, Belgrade + Faculty of Medicine, Belgrade)
Introduction. Special entities like solitary bone plasmocytoma (SBP) or
extramedullary plasmacytoma (EMP) can be found in a less than 5% of patients
with plasma cell disorders. EMP of the tongue represents very rare
localization of the head and neck plasmacytoma. Case report. We report a
case of 78-years-old woman who developed EMP of the tongue base detected by
the magnetic resonance imaging (MRI) of the head and neck region.
Immunohistochemical profile of the tumor tissue biopsy (CD38, IgG, kappa
positivity) indicated diagnosis of EMP. The diagnosis was established with
additional staging which confirmed the absence of other manifestation of the
disease. The patient was treated with 40 Gy of radiotherapy in 20 doses
resulting in the achievement of the complete remission of the disease. This
case was discussed with the reference to the literature. Conclusion. EMP of
the tongue base is a very rare entity of plasma cell dyscrasias. Appropriate
irradiation results in the achievement of a long-term remission and a
potential cure of the disease.
Keywords: plasmacytoma, diagnosis, tongue, radiotherapy, treatment outcome