Medicinski pregled 2010 Volume 63, Issue 5-6, Pages: 409-413
https://doi.org/10.2298/MPNS1006409K
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Body mass index in asthmatic children before and after one year inhaled glucocorticosteroids therapy BMI
Kostić Gordana
Ilić Nevenka
Petrović Marina
Marković Slavica
Vuletić Biljana
Igrutinović Zoran
Introduction. Asthma is the most frequent children’s disease, with a tendency
of further growth. Bearing in mind controversial data on obesity of asthmatic
children and a possible effect of inhaled corticosteroids (ICS) on children’s
growth, the aim of our study was to determine the body mass index (BMI) in
asthmatic children at the beginning of the therapy and to study the effect of
the continuous application of ICS on growth and BMI during the period of 1
year. Material and methods. The study included 100 children aged 7 to 18
diagnosed to have partly controlled and uncontrolled allergic asthma, who
were continuously given ICS as a prevention against asthma attacks at
Pediatric Clinic of the Clinical Center in Kragujevac for the period of 1
year. Children with BMI < p10 by their age and gender were considered to be
underweight, children with p10-84 as of normal weight, children with p85-97
as overweight and children with BMI >p97 as obese. Results. The highest
percentage of children with asthma was within normal parameters (70%), 10%
of the children were underweight (boys: n=8/60, 13.3% vs. girls: n=2/40, 5%),
and 18% were overweight/obese. Monovariable analysis of variant with
repeated measurements have shown a statistically significant difference in
the height of children in all age groups after a year of continuous therapy
of ICS (p=0.000), except in girls aged 15-18, who did not show any
significant difference in body height after the therapy (p>0.05). Conclusion.
Asthmatic children with partly controlled and uncontrolled asthma have mostly
normal BMI and ICS can be safely administered in asthmatic children.
Keywords: Body Mass Index, Child, Asthma, Glucocorticoids, Administration, Inhalation
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