doiSerbia

Influenza A and B viruses in the population of Vojvodina, Serbia

Radovanov J. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)
Milošević V. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)
Hrnjaković I. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)
Petrović V. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)
Ristić M. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)
Elez I. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)
Petrović T. (Scientific Veterinary Institute Novi Sad, Novi Sad)
Stefan-Mikić S. (Clinical Centre of Vojvodina, Clinic for Infectious Diseases Novi Sad, Medical Faculty, Novi Sad)
Patić A. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)
Jovanović-Galović A. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)
Đilas M. (Institute of Public Health of Vojvodina, Medical Faculty, Novi Sad)

At present, two influenza A viruses, H1N1pdm09 and H3N2, along with influenza B virus co-circulate in the human population, causing endemic and seasonal epidemic acute febrile respiratory infections, sometimes with life-threatening complications. Detection of influenza viruses in nasopharyngeal swab samples was done by real-time RT-PCR. There were 60.2% (53/88) positive samples in 2010/11, 63.4% (52/82) in 2011/12, and 49.9% (184/369) in 2012/13. Among the positive patients, influenza A viruses were predominant during the first two seasons, while influenza B type was more active during 2012/13. Subtyping of influenza A positive samples revealed the presence of A (H1N1)pdm09 in 2010/11, A (H3N2) in 2011/12, while in 2012/13, both subtypes were detected. The highest seroprevalence against influenza A was in the age-group 30-64, and against influenza B in adults aged 30-64 and >65.

Keywords: Influenza, acute respiratory infections, epidemic, pandemic, real-time PCR, seroprevalence

Projekat Ministarstva nauke Republike Srbije, br. TR31084