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Relationship between in-hospital mortality and creatinine/albumin in patients with ST-elevation myocardial infarction without standard modifiable risk factors

    Mehmet F Yılmaz

    *Author for correspondence: Tel.: +90 506 773 7732;

    E-mail Address: fthylmz1987@gmail.com

    Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, 34668, Turkey

    ,
    Ali Karagöz

    Department of Cardiology, Kosuyolu Kartal Heart Training and Research Hospital, Istanbul, 34865, Turkey

    ,
    Gönül Zeren

    Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, 34668, Turkey

    ,
    İlhan İ Avcı

    Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, 34668, Turkey

    ,
    Barış Timur

    Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, 34668, Turkey

    ,
    Mustafa A Sungur

    Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, 34668, Turkey

    ,
    Sedat Kalkan

    Department of Cardiology, Kosuyolu Kartal Heart Training and Research Hospital, Istanbul, 34865, Turkey

    ,
    Barış Şimşek

    Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, 34668, Turkey

    ,
    Fatma Can

    Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, 34668, Turkey

    ,
    Emrah Acar

    Department of Cardiology, Kosuyolu Kartal Heart Training and Research Hospital, Istanbul, 34865, Turkey

    ,
    İbrahim H Tanboğa

    Department of Cardiology, Hisar Intercontinental Hospital, Istanbul, 34768, Turkey

    Department of Cardiology, School of Health Science, Nisantası University, İstanbul, 34398, Turkey

    &
    Can Y Karabay

    Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, İstanbul, 34668, Turkey

    Published Online:https://doi.org/10.2217/bmm-2022-0241

    Background: Diabetes, hypertension, hyperlipidemia and smoking are associated with coronary artery disease and ST-elevation myocardial infarction (STEMI). However, patients without any classic risk factors have a higher mortality rate in the post-STEMI period. The aim of this study was to investigate the relationship between in-hospital mortality and creatinine/albumin ratio in patients with STEMI without modifiable risk factors. Materials & methods: All patients included in this study with a diagnosis of STEMI and who underwent primary percutaneous intervention between 2016 and 2020 were retrospectively analyzed. Patients were included in the standard modifiable cardiovascular risk factor (SMuRF) group if at least diabetes, hypertension, smoking or hyperlipidemia was present according to risk factors. Patients without these risk factors were considered the non-SMuRF group. Results: Creatinine/albumin ratio was found to be higher in non-SMuRF patients with mortality (p < 0.001). In multivariate logistic regression analysis, ejection fraction, hemoglobin and SMuRF were found to be inversely associated with in-hospital mortality (odds ratio [OR]: 0.48, 95% CI: 0.35–0.66, p < 0.001; OR: 0.70, 95% CI: 0.56–0.88, p = 0.002; OR: 0.57, 95% CI: 0.34–0.95, p = 0.03, respectively). Conclusion: The creatinine/albumin ratio can be used as a predictor of mortality in these patients; it can help identify high-risk patients beforehand.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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