We use cookies to improve your experience. By continuing to browse this site, you accept our cookie policy.×
Skip main navigation
Aging Health
Bioelectronics in Medicine
Biomarkers in Medicine
Breast Cancer Management
CNS Oncology
Colorectal Cancer
Concussion
Epigenomics
Future Cardiology
Future Medicine AI
Future Microbiology
Future Neurology
Future Oncology
Future Rare Diseases
Future Virology
Hepatic Oncology
HIV Therapy
Immunotherapy
International Journal of Endocrine Oncology
International Journal of Hematologic Oncology
Journal of 3D Printing in Medicine
Lung Cancer Management
Melanoma Management
Nanomedicine
Neurodegenerative Disease Management
Pain Management
Pediatric Health
Personalized Medicine
Pharmacogenomics
Regenerative Medicine

miRNAs as biomarkers of adverse drug reactions to platinum-based agents in patients with non-small-cell lung cancer

    Pedro ENS Vasconcelos

    School of Medical Sciences, University of Campinas, Campinas, 13083-887, Brazil

    ,
    Marília B Visacri

    School of Medical Sciences, University of Campinas, Campinas, 13083-887, Brazil

    ,
    Eder de C Pincinato

    School of Medical Sciences, University of Campinas, Campinas, 13083-887, Brazil

    ,
    Nadine de G Torso

    School of Medical Sciences, University of Campinas, Campinas, 13083-887, Brazil

    ,
    Cecília S Seguin

    School of Medical Sciences, University of Campinas, Campinas, 13083-887, Brazil

    ,
    Lair Zambon

    School of Medical Sciences, University of Campinas, Campinas, 13083-887, Brazil

    ,
    Aristóteles de S Barbeiro

    School of Medical Sciences, University of Campinas, Campinas, 13083-887, Brazil

    ,
    Maurício WP Junior

    School of Medical Sciences, University of Campinas, Campinas, 13083-887, Brazil

    &
    Patricia Moriel

    *Author for correspondence:

    E-mail Address: patricia.moriel@fcf.unicamp.br

    Faculty of Pharmaceutical Sciences, University of Campinas, Campinas, 13083-871, Brazil

    Published Online:https://doi.org/10.2217/bmm-2021-0443
    Free first page

    References

    • 1. Sung H, Ferlay J, Siegel RL et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 71, 209–249 (2021).
    • 2. Zheng M. Classification and pathology of lung cancer. Surg. Oncol. Clin. N. Am. 25, 447–468 (2016).
    • 3. Brasil. Ministério da Saúde. Secretaria de Atenção à Saúde. Protocolos clínicos e diretrizes terapêuticas em oncologia (2014). http://bvsms.saude.gov.br/bvs/publicacoes/protocolos_clinicos_diretrizes_terapeuticas_oncologia.pdf
    • 4. Caley ACR, Jones R. The principles of cancer treatment by chemotherapy. Surgery (Oxford) 30, 186–190 (2012).
    • 5. World Health Organization. Glossary. In: Safety Monitoring of Medical Products: Reporting system for the general public (2012). https://www.who.int/medicines/areas/quality_safety/safety_efficacy/EMP_ConsumerReporting_web_v2.pdf”
    • 6. Dasari S, Tchounwou PB. Cisplatin in cancer therapy: molecular mechanisms of action. Eur. J. Pharmacol. 740, 364–378 (2014).
    • 7. de Castria TB, da Silva EM, Gois AF et al. Cisplatin versus carboplatin in combination with third-generation drugs for advanced non-small-cell lung cancer. Cochrane Database Syst. Rev. 8, CD009256 (2013).
    • 8. Visacri MB, Ferrari GB, Dias P et al. Quality of life of patients with squamous cell carcinoma of the head and neck receiving high-dose cisplatin chemotherapy and radiotherapy. South. Med. J. 108, 343–349 (2015).
    • 9. Griesinger F, Korol EE, Kayaniyil S et al. Efficacy and safety of first-line carboplatin-versus cisplatin-based chemotherapy for non-small-cell lung cancer: a meta-analysis. Lung Cancer 135, 196–204 (2019).
    • 10. Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11, 597–610 (2010).
    • 11. Wang W, Shi Q, Mattes WB et al. Translating extracellular microRNA into clinical biomarkers for drug-induced toxicity: from high-throughput profiling to validation. Biomark. Med. 9, 1177–1188 (2015).
    • 12. Koturbash I, Tolleson WH, Guo L et al. MicroRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment. Biomark. Med. 9, 1153–1176 (2015).
    • 13. Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan – a web and mobile app for systematic reviews. Syst. Rev. 5, 210 (2016).
    • 14. Fang C, Li XP, Gong WJ et al. Age-related common miRNA polymorphism associated with severe toxicity in lung cancer patients treated with platinum-based chemotherapy. Clin. Exp. Pharmacol. Physiol. 44(Suppl. 1), 21–29 (2017).
    • 15. Pavkovic M, Robinson-Cohen C, Chua AS et al. Detection of drug-induced acute kidney injury in humans using urinary KIM-1, miR-21, -200c, and -423. Toxicol. Sci. 152, 205–213 (2016).
    • 16. Quintanilha JCF, Cursino MA, Borges JB et al. MiR-3168, miR-6125, and miR-4718 as potential predictors of cisplatin-induced nephrotoxicity in patients with head and neck cancer. BMC Cancer 21, 575 (2021).