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Preliminary Communication

Association of IGF-1 with coronary collateral circulation in stable coronary artery disease

    Harun Kundi

    *Author for correspondence:

    E-mail Address: harunkundi@hotmail.com

    Cardiology Department, Ankara Numune Education & Research Hospital, Ankara, Turkey

    ,
    Murat Gok

    Cardiology Department, Ankara Numune Education & Research Hospital, Ankara, Turkey

    ,
    Emrullah Kiziltunc

    Cardiology Department, Ankara Numune Education & Research Hospital, Ankara, Turkey

    ,
    Mustafa Cetin

    Cardiology Department, Ankara Numune Education & Research Hospital, Ankara, Turkey

    &
    Ender Ornek

    Cardiology Department, Ankara Numune Education & Research Hospital, Ankara, Turkey

    Published Online:https://doi.org/10.2217/bmm-2016-0354

    Aim: The aim of the present study is to evaluate the relationship between coronary collateral circulation (CCC) grade and serum IGF-1 levels in patients diagnosed with stable coronary artery disease. Methods: Totally, 190 consecutive patients with stable coronary artery disease who underwent coronary angiography were included in this study. Results: The patients with good CCC had significantly higher IGF-1 levels compared with the poor ones. On the contrary, hs-CRP was significantly lower in the good CCC group. We also demonstrated that IGF-1 level was significantly related with the grade of CCC. Conclusion: We believe that measurement of IGF-1 level may help clinicians for predicting CCC development.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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