PDB Entry - 4V26

(Status - Released)

Summary information:

Title: VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context- dependent cytostasis in cancer cells

PDB DOI: https://doi.org/10.2210/pdb4v26/pdb

Primary publication DOI: https://doi.org/10.18632/oncotarget.2656

Entry authors: Moore, J.D., Staniszewska, A., Shaw, T., D'Alessandro, J., Davis, B., Surgenor, A., Baker, L., Matassova, N., Murray, J., Macias, A., Brough, P., Wood, M., Mahon, P.C.

Initial deposition on: 6 October 2014

Initial release on: 3 December 2014

Latest revision on: 9 October 2019

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (XML)

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