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Accepted for/Published in: JMIR Formative Research

Date Submitted: Jul 8, 2022
Open Peer Review Period: Jul 8, 2022 - Sep 2, 2022
Date Accepted: Mar 23, 2023
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Patient-Centered Outcomes Associated With a Novel Office-Based Opioid Treatment Program in a District Health Department: Mixed Methods Pilot Study

Coles T, Chen H, Des Marais A, Sachdeva N, Bush C, Macon Harrison L, Guthrie S

Patient-Centered Outcomes Associated With a Novel Office-Based Opioid Treatment Program in a District Health Department: Mixed Methods Pilot Study

JMIR Form Res 2023;7:e40897

DOI: 10.2196/40897

PMID: 37223963

PMCID: 10248770

Patient-Centered Outcomes associated with a Novel Office-Based Opioid Treatment Program in a District Health Department: A Mixed-Method Pilot Study

  • Theresa Coles; 
  • Hillary Chen; 
  • Andrea Des Marais; 
  • Nidhi Sachdeva; 
  • Christopher Bush; 
  • Lisa Macon Harrison; 
  • Shauna Guthrie

ABSTRACT

Background:

Granville and Vance counties have some of the highest opioid-related death rates in North Carolina, and have significant unmet needs with regard to opioid treatment. In order to connect patients with needed medication for opioid use disorder (MOUD) services, the district health department, Granville Vance Public Health (GVPH), established an office-based opioid treatment (OBOT) program.

Objective:

In this formative pilot study, we sought to describe patients’ goals and outcomes in a program delivered at a rural local health department using an integrated care approach.

Methods:

We used a mixed-methods concurrent nested research design. The primary method of investigation was one-on-one qualitative interviews with active OBOT patients (n=7) focused on patients’ goals and perceived impacts of the program. The secondary method was a descriptive quantitative analysis (n=79 patients; 1478 visits over 2.5 years) of treatment retention, and patient-reported outcomes.

Results:

Participants in the OBOT program were 39.6 years old on average, and 25.3% were uninsured. Average retention in the program was 18.4 months. The proportion of individuals in the program with moderate-to-severe depression (Patient Health Questionnaire-9 scores ≥10) at program initiation was 66%, and at the most-recent assessment, reduced to 34%. Patients credited the OBOT program for reductions in use of opioids and other substances, and improvements in quality of life.

Conclusions:

Initial data show promising patient outcomes for active GVPH OBOT participants, including reduction in opioid use and improvements in quality of life. As a pilot study, a limitation of this study is a lack of a comparison group. However, this formative project demonstrates promising patient-centered outcome improvements for GVPH OBOT participants. Clinical Trial: n/a


 Citation

Please cite as:

Coles T, Chen H, Des Marais A, Sachdeva N, Bush C, Macon Harrison L, Guthrie S

Patient-Centered Outcomes Associated With a Novel Office-Based Opioid Treatment Program in a District Health Department: Mixed Methods Pilot Study

JMIR Form Res 2023;7:e40897

DOI: 10.2196/40897

PMID: 37223963

PMCID: 10248770

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© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.

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