Captagon Use in a Patient with Iatrogenic Opioid Use Disorder

Title:Captagon Use in a Patient with Iatrogenic Opioid Use Disorder

Volume: 10

Author(s): Mohammed Hamdan, Samer El Hayek and Maya Bizri*

Affiliation:

• Department of Psychiatry, American University of Beirut, Beirut,Lebanon

Keywords: Captagon, acute intoxication, opioid withdrawal, consultation-liaison psychiatry, iatrogenic opioid, theophylline derivative.

Abstract:

Background: Captagon or Fenethylline is a synthetic theophylline derivative of amphetamine that is widely available for recreational use in the Middle East. It has pain-reducing properties and is known to induce restlessness, irritability, and psychotic symptoms.

Case Presentation: A middle-aged man with iatrogenic opioid use disorder was admitted for acute cholecystitis. A week following cholecystectomy, the patient used Captagon while hospitalized to manage opioid withdrawal pain. He experienced waxing and waning episodes of irritability, aggressiveness, disorganized behaviors, delusions, and hallucinations, all concurrent with his Captagon intake. These episodes were managed similarly to intoxication with other stimulant types.

Conclusion: Careful patient counseling and close follow-up are essential when opioids are prescribed. Captagon’s pain-reducing properties make it an attractive and dangerous option for Middle Eastern patients suffering from opioid withdrawal. Captagon intoxication is currently managed similarly to other stimulant types, but more studies are needed to develop management guidelines specific to this substance.

Cite this article as:

Hamdan Mohammed , El Hayek Samer and Bizri Maya*, Captagon Use in a Patient with Iatrogenic Opioid Use Disorder, Current Psychopharmacology 2021; 10 (3) : e010721194414 . https://dx.doi.org/10.2174/2211556010666210701163649