Abstract
Telocytes (TCs) are a newly identified interstitial cell type which are named after and characterized by specialized thin, long synaptic structures called telopodes (Tps). The existence of TCs has been reported in lots of tissues and organs. There are numerous on-going studies to explore the biological functions of TCs, including their involvement in human disease. TCs are generally considered as supporting cells that help maintain the micro-structure of tissues by forming a three-dimensional interstitial network via intercellular junctions. In addition, TCs have also been implicated in the regulation of stem cell activity and the stem cell niche microenvironment, thus contributing to tissue repair and renewal. In this review, the most recent findings concerning hepatic TCs are described.
Keywords: Telocytes, liver, regeneration, fibrosis.
Current Stem Cell Research & Therapy
Title:Telocytes in Liver
Volume: 11 Issue: 5
Author(s): Jingqi Liu, Yan Cao, Yang Song, Qi Huang, Fei Wang, Wenzhuo Yang and Changqing Yang
Affiliation:
Keywords: Telocytes, liver, regeneration, fibrosis.
Abstract: Telocytes (TCs) are a newly identified interstitial cell type which are named after and characterized by specialized thin, long synaptic structures called telopodes (Tps). The existence of TCs has been reported in lots of tissues and organs. There are numerous on-going studies to explore the biological functions of TCs, including their involvement in human disease. TCs are generally considered as supporting cells that help maintain the micro-structure of tissues by forming a three-dimensional interstitial network via intercellular junctions. In addition, TCs have also been implicated in the regulation of stem cell activity and the stem cell niche microenvironment, thus contributing to tissue repair and renewal. In this review, the most recent findings concerning hepatic TCs are described.
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Cite this article as:
Liu Jingqi, Cao Yan, Song Yang, Huang Qi, Wang Fei, Yang Wenzhuo and Yang Changqing, Telocytes in Liver, Current Stem Cell Research & Therapy 2016; 11 (5) . https://dx.doi.org/10.2174/1574888X10666150630112035
DOI https://dx.doi.org/10.2174/1574888X10666150630112035 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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