Abstract
Myocardial tissue engineering involves the design of biomaterial scaffolds, aiming at regenerating necrotic myocardium after myocardial infarction. Biomaterials provide mechanical support to the infarct area and they can be used as vehicles for sustained and controlled local administration of cells and growth factors. Although promising results have been reported in experimental studies, many issues need to be addressed before human use.
Keywords: Biomaterial scaffold, cardiac repair, heart failure, myocardial infarction, ventricular remodeling, tissue engineering, necrotic, Hypertrophy, Infarct Healing, Gelatin, Nano-Clays, Alginate
Mini-Reviews in Medicinal Chemistry
Title: Tissue Engineering for Post-Myocardial Infarction Ventricular Remodeling
Volume: 11 Issue: 3
Author(s): T. M. Kolettis, A. Vilaeti, K. Dimos, N. Tsitou and S. Agathopoulos
Affiliation:
Keywords: Biomaterial scaffold, cardiac repair, heart failure, myocardial infarction, ventricular remodeling, tissue engineering, necrotic, Hypertrophy, Infarct Healing, Gelatin, Nano-Clays, Alginate
Abstract: Myocardial tissue engineering involves the design of biomaterial scaffolds, aiming at regenerating necrotic myocardium after myocardial infarction. Biomaterials provide mechanical support to the infarct area and they can be used as vehicles for sustained and controlled local administration of cells and growth factors. Although promising results have been reported in experimental studies, many issues need to be addressed before human use.
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Cite this article as:
M. Kolettis T., Vilaeti A., Dimos K., Tsitou N. and Agathopoulos S., Tissue Engineering for Post-Myocardial Infarction Ventricular Remodeling, Mini-Reviews in Medicinal Chemistry 2011; 11 (3) . https://dx.doi.org/10.2174/138955711795049853
DOI https://dx.doi.org/10.2174/138955711795049853 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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