Generic placeholder image

Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Cell Death in the IPLB-LdFB Insect Cell Line: Facts and Implications

Author(s): D. Malagoli

Volume 14, Issue 2, 2008

Page: [126 - 130] Pages: 5

DOI: 10.2174/138161208783378752

Price: $65

Abstract

The present review summarizes findings on stress-induced cell death in the IPLB-LdFB insect cell line derived from the larval fat body of the lepidopteron Lymantria dispar. Apoptotic, oncotic and autophagic cell death have been described in these cells as a consequence of oxidative stress or ATP deprivation, and similarities between IPLB-LdFB and mammalian apoptotic pathways have been highlighted. Furthermore, starting from observations in the IPLB-LdFB cells, a link has been surmised between relevance of autophagic cell death and developmental processes in the metazoan taxa.

Keywords: IPLB-LdFB insect cell line, Apoptosis, Oncosis, Autophagic cell death


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy