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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Radiolabeled Glucose Derivatives for Tumor Imaging Using SPECT and PET

Author(s): T. Liu, J. Zhang, X. Wang, J. Yang, Z. Tang and J. Lu

Volume 21, Issue 1, 2014

Page: [24 - 34] Pages: 11

DOI: 10.2174/09298673113209990254

Price: $65

Abstract

Glucose is an important molecule for metabolism. It is more actively taken up in tumor cells than in normal cells, thus making it possible to detect the tumor. Radiolabeled glucose derivates have been successfully employed for tumor imaging for several decades. This review focuses on the development of various radiolabeled glucose derivatives as tumor imaging probes with single photon emission computed tomography (SPECT) and positron emission tomography (PET) and discusses basic research data, current status and future prospects of this class of imaging agents.

Keywords: Glucose derivatives, PET, radiotracers, SPECT, tumor imaging.


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