Renal Failure Found during the Follow-up of Sarcoidosis: The Relevance of a Delay in the Diagnosis of Concurrent Hypercalcemia

Erika Hishida; Takahiro Masuda; Tetsu Akimoto; Ryuta Sato; Natsuko Wakabayashi; Atsushi Miki; Naoko Otani; Toshimi Imai; Taro Sugase; Shin-ichi Takeda; Shigeaki Muto; Daisuke Nagata

doi:10.2169/internalmedicine.55.6194

CASE REPORTS

Renal Failure Found during the Follow-up of Sarcoidosis: The Relevance of a Delay in the Diagnosis of Concurrent Hypercalcemia

Erika Hishida, Takahiro Masuda, Tetsu Akimoto, Ryuta Sato, Natsuko Wakabayashi, Atsushi Miki, Naoko Otani, Toshimi Imai, Taro Sugase, Shin-ichi Takeda, Shigeaki Muto, Daisuke Nagata

Author information

Erika Hishida
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Takahiro Masuda
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Tetsu Akimoto
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Ryuta Sato
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Natsuko Wakabayashi
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Atsushi Miki
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Naoko Otani
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Toshimi Imai
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Taro Sugase
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Shin-ichi Takeda
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Shigeaki Muto
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan
Daisuke Nagata
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan

Keywords: hypercalcemia, hypercalciuria, ocular sarcoidosis, hydronephrosis, chronic kidney disease

JOURNAL OPEN ACCESS

2016 Volume 55 Issue 14 Pages 1893-1898

DOI https://doi.org/10.2169/internalmedicine.55.6194

Details

Abstract

We herein present a case of relapsed sarcoidosis with a deteriorated renal function accompanied by hypercalcemia, nephrolithiasis, and a ureteral stone in a woman with a history of ocular sarcoidosis. The ocular involvement appeared to be well controlled for a long period of time with a topical ophthalmic steroid; however, we believe that the absence of apparent recrudescence could have led to the delay in our diagnosis of relapse of the disease during the follow-up period. The conundrums regarding longitudinal surveillance for both evaluating the disease activity and determining the necessity of therapeutics are also discussed.

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