Periodic Peritonitis due to Familial Mediterranean Fever in a Patient with Systemic Lupus Erythematosus

Masayuki Matsuda; Dai Kishida; Ayako Tsuchiya-Suzuki; Kazuhiro Fukushima; Yasuhiro Shimojima; Masahide Yazaki; Shu-ichi Ikeda

doi:10.2169/internalmedicine.49.4043

CASE REPORTS

Periodic Peritonitis due to Familial Mediterranean Fever in a Patient with Systemic Lupus Erythematosus

Masayuki Matsuda, Dai Kishida, Ayako Tsuchiya-Suzuki, Kazuhiro Fukushima, Yasuhiro Shimojima, Masahide Yazaki, Shu-ichi Ikeda

Author information

Keywords: systemic lupus erythematosus, familial Mediterranean fever, MEFV gene, colchicine, peritonitis

JOURNAL OPEN ACCESS

2010 Volume 49 Issue 20 Pages 2259-2262

DOI https://doi.org/10.2169/internalmedicine.49.4043

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Abstract

We report a patient with systemic lupus erythematosus (SLE) who showed periodic peritonitis with spontaneous remission. She showed compound heterozygous mutations in the MEFV gene, leading to the diagnosis of familial Mediterranean fever (FMF). Oral colchicine successfully reduced the severity and frequency of her peritonitis. SLE occasionally manifests abdominal symptoms, but in cases with periodic peritonitis, associated FMF should be considered as a possible cause.

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