Pulmonary Cryptococcosis with a Solitary Focal Ground-glass Opacity on High-resolution Computed Tomography

Mitsuo SATO; Masakazu OKAMOTO; Yasuyuki TAKAGI; Takuya IKEDA; Takao NIIMI; Eriko FUKATSU; Kunihiro MARUYAMA; Yoshiharu NARA; Kaoru SHIMOKATA; Yoshinori HASEGAWA

doi:10.2169/internalmedicine.43.117

Respiratory Diseases

Pulmonary Cryptococcosis with a Solitary Focal Ground-glass Opacity on High-resolution Computed Tomography

Mitsuo SATO, Masakazu OKAMOTO, Yasuyuki TAKAGI, Takuya IKEDA, Takao NIIMI, Eriko FUKATSU, Kunihiro MARUYAMA, Yoshiharu NARA, Kaoru SHIMOKATA, Yoshinori HASEGAWA

Author information

Mitsuo SATO
Departments of Respiratory Disease, Yokkaichi Municipal Hospital
Masakazu OKAMOTO
Departments of Respiratory Disease, Yokkaichi Municipal Hospital
Department of Pulmonary Medicine, Nagoya University School of Medicine
Yasuyuki TAKAGI
Departments of Respiratory Disease, Yokkaichi Municipal Hospital
Takuya IKEDA
Departments of Respiratory Disease, Yokkaichi Municipal Hospital
Takao NIIMI
Departments of Thoracic Surgery, Yokkaichi Municipal Hospital
Eriko FUKATSU
Departments of Radiology, Yokkaichi Municipal Hospital
Kunihiro MARUYAMA
Departments of Radiology, Yokkaichi Municipal Hospital
Yoshiharu NARA
Departments of Pathology, Yokkaichi Municipal Hospital
Kaoru SHIMOKATA
Department of Pulmonary Medicine, Nagoya University School of Medicine
Yoshinori HASEGAWA
Department of Pulmonary Medicine, Nagoya University School of Medicine

Keywords: pulmonary cryptococcosis, Cryptococcus neoformans, natural history, video-assisted thoracic surgery, solitary focal ground-glass opacity, high-resolution computed tomography

JOURNAL OPEN ACCESS

2004 Volume 43 Issue 2 Pages 117-119

DOI https://doi.org/10.2169/internalmedicine.43.117

Details

Abstract

We report a 74-year-old woman with cervical cancer who developed pulmonary cryptococcosis which presented as a solitary focal ground-glass opacity (GGO) on high-resolution computed tomography (HRCT). Serial HRCT showed the progression from the GGO to a discrete solid nodule. We hypothesize that the initial GGO may correspond pathologically to partial filling of air spaces with cryptococcal organisms and inflammatory cells. To our knowledge, this is the first report of pulmonary cryptococcosis with a solitary focal GGO on HRCT in the literature.

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