A Young Female Case of Polyarteritis Nodosa Strongly Suspected by Typical Angiographic Findings Which Improved Rapidly after Prednisolone and Cyclophosphamide Therapy

Hideo YAMADA; Masashi OKA; Seiko MORI; Takeshi TAKAHASHI; Shoji KUWATA; Chikara AIZAWA; Gotaro TODA; Kiyoshi KUROKAWA

doi:10.2169/internalmedicine.31.431

Hideo YAMADA, Masashi OKA, Seiko MORI, Takeshi TAKAHASHI, Shoji KUWATA, Chikara AIZAWA, Gotaro TODA, Kiyoshi KUROKAWA

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Hideo YAMADA
the First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Masashi OKA
the First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Seiko MORI
the First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Takeshi TAKAHASHI
the First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Shoji KUWATA
the First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Chikara AIZAWA
the First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Gotaro TODA
the First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Kiyoshi KUROKAWA
the First Department of Internal Medicine, Faculty of Medicine, University of Tokyo

Keywords: hypertension, micro-aneurysm

JOURNAL FREE ACCESS

1992 Volume 31 Issue 3 Pages 431-433

DOI https://doi.org/10.2169/internalmedicine.31.431

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Abstract

A 16-year-old girl was admitted with the complaints of headache, chest pain, low abdominal pain and left hemi-numbness. Her blood pressure was high and plasma renin activity and aldosterone levels were elevated. Renal angiography revealed vascular stenoses and microaneurysms although the renal artery and its main branches were not involved. Polyarteritis nodosa (PN) was strongly suspected and oral prednisolone and intravenous pulse therapy of cyclophosphamide were started. The second renal angiography which was performed 11 days after the therapy was started, showed marked improvement of vascular lesions. This is a case which suggests that the angiographic findings of PN can improve very rapidly with therapy.
(Internal Medicine 31 : 431-433, 1992)

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