Metallomics approach to changes in element concentration during differentiation from fibroblasts into adipocytes by element array analysis

Yasumitsu Ogra; Shu Nagasaki; Ayako Yawata; Yasumi Anan; Koichi Hamada; Akihiro Mizutani

doi:10.2131/jts.41.241

Letter

Metallomics approach to changes in element concentration during differentiation from fibroblasts into adipocytes by element array analysis

Yasumitsu Ogra, Shu Nagasaki, Ayako Yawata, Yasumi Anan, Koichi Hamada, Akihiro Mizutani

Author information

Keywords: Metallomics, Differentiation, Fibroblast, Adipocyte, 3T3-L1

JOURNAL FREE ACCESS

2016 Volume 41 Issue 2 Pages 241-244

DOI https://doi.org/10.2131/jts.41.241

Details

Abstract

We aimed to establish an element array analysis that involves the simultaneous detection of all elements in cells and the display of changes in element concentration before and after a cellular event. In this study, we demonstrated changes in element concentration during the differentiation of 3T3-L1 mouse fibroblasts into adipocytes. This metallomics approach yielded unique information of cellular response to physiological and toxicological events.

Corresponding author

Register with J-STAGE for free!