Abstract
Nickel microspheres were synthesized via a water-in-oil reverse nanoemulsion system using nickel nitrate as the nickel precursor and hydrazine hydrate as the reducing agent. The nanoemulsion was a triton X-100/cyclohexane/water ternary system. The surface morphology of the nickel microspheres was studied by scanning electron microscopy, which indicated that the microspheres had a nanoporous structure. The electrochemical behavior of the nanoporous nickel microspheres were studied in alkaline solution and were then employed to fabricate a modified carbon paste electrode in order to investigate the electrocatalytic oxidation of the drug acyclovir. The oxidation process involved, and its kinetics were investigated using cyclic voltammetry and chronoamperometry. The rate constant of the catalytic oxidation of acyclovir and the electron-transfer coefficient are reported. A sensitive, simple and time-saving amperometric procedure was developed for the analysis of acyclovir. The proposed amperometric method was also applied to determine acyclovir in tablets and topical cream.
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P. Zijlstra and M. Orrit, Rep. Prog. Phys., 2011, 74, Article Number: 106401.
B. M. Munoz-Flores, B. I. Kharisov, V. M. Jimenez-Perez, P. E. Martinez, and S. T. Lopez, Ind. Eng. Chem. Res., 2011, 50, 7705.
S. J. Guo and E. K. Wang, Nano Today, 2011, 6, 240.
G. Thirumurugan and M. D. Dhanaraju, Adv. Sci. Lett., 2011, 4, 339.
E. Comini and G. Sberveglieri, Mater. Today, 2010, 13, 28.
A. Kolmakov and M. Moskovits, Annu. Rev. Mater. Res., 2004, 34, 151.
N. Sattarahmady, H. Heli, and F. Faramarzi, Talanta, 2010, 82, 1126.
K. R. Prasad and N. Miura, Appl. Phys. Lett., 2004, 85, 4199.
L. D. Rafailovic and D. M. Minic, Hemijska Industrija, 2009, 63, 557.
N. Sattarahmady, H. Heli, and A. A. Moosavi-Movahedi, Biosens. Bioelectron., 2010, 25, 2329.
Z. W. Shi and A. V. Walker, Langmuir, 2011, 27, 11292.
N. Chopra, W. W. Shi, and A. Bansal, Carbon, 2011, 49, 3645.
M. Cabo, S. Garroni, E. Pellicer, C. Milanese, A. Girella, A. Marini, E. Rossinyol, S. Surinach, and M. D. Baro, Int. J. Hydrogen Energy, 2011, 36, 5400.
T. R. Ling, C. S. Li, J. J. Jow, and J. F. Lee, Electrochim. Acta, 2011, 56, 1043.
J. H. Li, C. C. Wang, C. J. Huang, Y. F. Sun, W. Z. Weng, and H. L. Wan, Appl. Catal., A, 2010, 382, 99.
S. K. Meher, P. Justin, and G. R. Rao, Electrochim. Acta, 2010, 55, 8388.
D. D. Zhao, W. J. Zhou, and H. L. Li, Chem. Mater., 2007, 19, 3882.
J. M. Gutiérrez, C. Gonzalez, A. Maestro, I. Sole, C. M. Pey, and J. Nolla, Curr. Opin. Colloid Interface Sci., 2008, 13, 245.
I. Capek, Adv. Colloid Interface Sci., 2004, 110, 49.
Z. Jia, W. Yujun, and L. Guangsheng, React. Funct. Polym., 2005, 65, 249.
A. K. Ganguli, A. Ganguly, and S. Vaidya, Chem. Soc. Rev., 2010, 39, 474.
I. Svancara, A. Walcarius, K. Kalcher, and K. Vytras, Central Eur. J. Chem., 2009, 7, 598.
H. Heli, A. Jabbari, S. Majdi, M. Mahjoub, A. A. Moosavi-Movahedi, and Sh. Sheibani, J. Solid State Electrochem., 2009, 13, 1951.
S. Majdi, A. Jabbari, H. Heli, and A. A. Moosavi-Movahedi, Electrochim. Acta, 2007, 52, 4622.
Y. Mu, D. Jia, Y. He, Y. Miao, and H.-L. Wu, Biosens. Bioelectron., 2011, 26, 2948.
E. Laviron, J. Electroanal. Chem., 1979, 101, 19.
H. Luo, Z. Shi, N. Li, Z. Gu, and Q. Zhuang, Anal. Chem., 2001, 73, 915.
M. Hajjizadeh, A. Jabbari, H. Heli, A. A. Moosavi-Movahedi, and S. Haghgoo, Electrochim. Acta, 2007, 53, 1766.
S. Berchmans, H. Gomathi, and G. P. Rao, J. Electroanal. Chem., 1995, 394, 267.
A. J. Bard and L. R. Faulkner, “Electrochemical Methods: Fundamentals and Applications”, 1980, John Wiley and Sons, New York.
K. C. Honeychurch, M. R. O’Donovan, and J. P. Hart, Biosens. Bioelectron., 2007, 22, 2057.
E. Gonzalez-Fernandez, N. de-los Santos-Alvarez, M. J. Lobo-Castanon, A. J. Miranda-Ordieres, and P. Tunon-Blanco, Electroanalysis, 2008, 20, 833.
O. Hammerich, J. H. P. Utley, and L. Eberson (ed.), “Organic Electrochemistry”, 1991, Marcel Dekker, New York.
J. A. Harrison and Z. A. Khan, J. Electroanal. Chem., 1970, 28, 131.
J. C. Miller and J. N. Miller, “Statistics for Analytical Chemistry”, 4th ed., 1994, Ellis-Horwood, New York.
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Heli, H., Pourbahman, F. & Sattarahmady, N. Nanoporous Nickel Microspheres: Synthesis and Application for the Electrocatalytic Oxidation and Determination of Acyclovir. ANAL. SCI. 28, 503–510 (2012). https://doi.org/10.2116/analsci.28.503
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DOI: https://doi.org/10.2116/analsci.28.503