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A Simple and Selective Sensor for the Determination of Ascorbic Acid in Vitamin C Tablets Based on Paptode

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Abstract

A method for the determination of ascorbic acid in vitamin C tablets based on a very simple paptode design on TLC strips is described. This procedure is based on the reduction of iron(III) with ascorbic acid and the formation of a colorful red complex with immobilized 2,2’-dipyridyl (dipy) on TLC strips. The linear range of the system was 20 - 200 ppm with a detection limit of 1 ppm and a relative standard deviation of 1.5% (w = 28). The parameters, such as pH, concentration of iron(III), concentration of dipy and the volume of dipy per 1 cm2 of TLC strips, were optimized. The proposed sensor was successfully applied for the determination of ascorbic acid in vitamin C tablets.

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References

  1. M. Levine, N. Engl. J. Med., 1986, 314, 892.

    Article  CAS  Google Scholar 

  2. S. H. R. Davis and S. J. Masten, Anal. Chim. Acta, 1991, 248, 225.

    Article  Google Scholar 

  3. Z. Zhang, and W. Qin, Talanta, 1996, 43, 119.

    Article  CAS  Google Scholar 

  4. X. Chen, and M. Sato, Anal. Sci., 1995, 11, 749.

    Article  CAS  Google Scholar 

  5. L. T. Jin, G. Z. Zhao, and Y. Z. Fang, Chem. J. Chin. Univ., 1994, 15, 189.

    CAS  Google Scholar 

  6. A. Jain, A. Chaurasia, and K. K. Verma, Talanta, 1995, 42, 779.

    Article  CAS  Google Scholar 

  7. J. Fan, C. L. Ye, S. L. Feng, G. Zhang, and J. J. Wang, Talanta, 1999, 50, 893.

    Article  CAS  Google Scholar 

  8. J. Wu, J. Suls, and W. Sansen, Electrochem. Commun., 2000, 2, 90.

    Article  CAS  Google Scholar 

  9. P. O. Barrales, M. L. F. de Cordova, and A. M. Diaz, Anal. Chim. Acta, 1998, 560, 143.

    Article  Google Scholar 

  10. S. P. Arya, M. Mahajan, and P. Jain, Anal. Chim. Acta, 2001, 427, 245.

    Article  CAS  Google Scholar 

  11. M. C. Yebra, R. M. Cespon, and A. Moreno-Cid, Anal. Chim. Acta, 2001, 448, 157.

    Article  CAS  Google Scholar 

  12. N. Gan, R. Cai, and Z. Lin, Anal. Chim. Acta, 2002, 466, 257.

    Article  CAS  Google Scholar 

  13. D. R. Shankaran, Sens. Actuators, B, 2003, 94, 73.

    Article  Google Scholar 

  14. D. G. Themelis, P. D. Tzanavaras, and F. S. Kika, Talanta, 2001, 55, 127.

    Article  CAS  Google Scholar 

  15. T. Kleszczewski, and E. Kleszczewska, J. Pharm. Biomed. Anal, 2002, 29, 755.

    Article  CAS  Google Scholar 

  16. K. Giiclii, K. Sozgen, E. Tiltem, M. Ozyiirek, and R. Apak, Talanta, 2005, 65, 1226.

    Article  Google Scholar 

  17. http://en.wikipedia.org/wiki/RGB_color_model.

  18. J. J. Lavigne, S. Savoy, M. B. Clevenger, J. E. Richie, B. McDoniel, S. J. Yoo, E. V. Anslyn, J. T. McDevitt, J. B. Shear, and D. Neikirk, J. Am. Chem. Soc, 1998, 120, 6429.

    Article  CAS  Google Scholar 

  19. A. Goodey, J. J. Lavigne, S. M. Savoy, M. D. Rodriguez, T. Curey, A. Taso, G. Simmons, J. Wright, S. J. Yoo, Y. Sohn, E. V. Anslyn, J. B. Shear, D. P. Neikirk, and J. T. McDevitt, J. Am. Chem. Soc, 2001, 123, 2559.

    Article  CAS  Google Scholar 

  20. A. Abbaspour, M. A. Mehrgardi, A. Noori, M. A. Kamyabi, A. Khalafi-Nezhad, and M. N. S. Rad, Sens. Actuators, B, 2006, 113, 857.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Chemistry Department, Shiraz University, Shiraz, 71454, Iran

    Abdolkarim Abbaspour, Abdolreza Khajehzadeh & Abolhassan Noori

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  1. Abdolkarim Abbaspour
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  2. Abdolreza Khajehzadeh
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  3. Abolhassan Noori
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Correspondence to Abdolkarim Abbaspour.

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Abbaspour, A., Khajehzadeh, A. & Noori, A. A Simple and Selective Sensor for the Determination of Ascorbic Acid in Vitamin C Tablets Based on Paptode. ANAL. SCI. 24, 721–725 (2008). https://doi.org/10.2116/analsci.24.721

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  • DOI: https://doi.org/10.2116/analsci.24.721

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