Abstract
In this paper, we firstly report the direct voltammetric recognition and determination of dopamine (DA) by using AlIII-DA complexes at the hanging mercury drop electrode (HMDE). A new sensitive cathodic peak of AlIII-DA can be detected at–900 mV (vs. SCE) in 0.1 M NH4Cl–NH3•H2O–0.1 M KCl buffer solution at pH 8.5. This unique–900 mV cathodic peak arises from the specific interaction between AlIII and DA on the HMDE, whereas other substances with similar structures, such as L-dopa, epinephrine (EP), norepinephrine (NE), catechols, caffeic acid (CA), trihydric phenols and tiron, do not yield any new peak on the voltammograms in the potential range from–100 to–1200 mV when AlIII is added. The distinct voltammetric characteristic of the recognition of DA can effectively inhibit the interferences of both ascorbic acid and uric acid in the DA determination by the direct electrochemistry, which is a major difficulty when a solid electrode is used. The proposed method can be anticipated as an effective means for the recognition of DA in the elucidation of the mechanisms of Parkinson’s disease (PD) and Alzheimer’s disease (AD) in the presence of AlIII.
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P. A. Garris, E. A. Budygin, P. E. M. Phillips, B. J. Venton, D. L. Robinson, B. P. Bergstrom, G. V. Rebec, and R. M. Wightman, Neuroscience, 2003, 118, 819.
D. R. Williams, J. Inorg. Biochem., 2000, 79, 275.
P. L. Runnels, J. D. Joseph, M. J. Logman, and R. M. Wightman, Anal. Chem., 1999, 71, 2782.
A. R. Bernardo, J. F. Stoddart, and A. E. Kaifer, J. Am. Chem. Soc., 1992, 114, 10624.
K. Pihel, T. J. Schroeder, and R. M. Wightman, Anal. Chem., 1994, 66, 4532.
C. D. Allred and R. L. McCreery, Anal. Chem., 1992, 64, 444.
T. G. Strein and A. G. Ewing, Anal. Chem., 1991, 63, 194.
R. Kalvoda, Anal. Chim. Acta, 1984, 162, 197.
R. Kalvoda, J. Electroanal. Chem., 1986, 214, 191.
A. Dalmia, C. C. Liu, and R. F. Savinell, J. Electroanal. Chem., 1997, 430, 205.
J. W. Mo and B. Ogorevc, Anal. Chem., 2001, 73, 1196.
S. H. DuVall and R. L. McCreery, Anal. Chem., 1999, 71, 4594.
J. M. Zen, G. Ilangovan, and J. J. Jou, Anal. Chem., 1999, 71, 2797.
A. Ciszewski and G. Milczarek, Anal. Chem., 1999, 71, 1055.
J. M. Zen and P. J. Chen, Anal. Chem., 1997, 69, 5087.
R. S. Deinhammer, M. Ho, J. W. Anderegg, and M. D. Porter, Langmiur, 1994, 10, 1306.
P. D. Lyne and R. D. O’Neill, Anal. Chem., 1990, 62, 2347.
M. L. McGlashen, K. L. Davis, and M. D. Morris, Anal. Chem., 1990, 62, 846.
A. J. Tudos, W. J. J. Ozinga, H. Poppe, and W. T. Kok, Anal. Chem., 1990, 62, 367.
L. M. Jesus, A. G. Josefa, and M. L. Juan, Talanta, 2001, 53, 721.
H. Obata and C. M. G. van den Berg, Anal. Chem., 2001, 73, 2522.
J. Limson and T. Nyokong, Anal. Chim. Acta, 1997, 344, 87.
K. Hasebe, S. Hikima, T. Kakizaki, T. Iwashimizu, and K. Aoki, Analyst, 1990, 115, 413.
L. M. Jesus, A. G. Josefa, and M. L. Juan, Electroanalysis, 1999, 11, 656.
X. X. Gao, “Polarographic Catalytic Waves,” 1991, Science Press, Beijing.
F. C. Meng, S. X. Li, and P. H. Zhao, “Adsorptive Wave and Catalytic Wave of Polarographic Complexes, ” 2001, Wuhan University Press.
F. P. Zhang, M. Ji, S. P. Bi, and L. Yang, J. Inorg. Biochem., 2005, 99, 1756.
J. W. Di and M. Jin, Analytical Labs (in Chinese), 1995, 14, 33.
C. Exley (ed.), “Aluminum and Alzheimer’s Disease—The Science That Describes the Link,” 2001, Elsevier, Amsterdam.
J. Liu, S. P. Bi, L. Yang, X. D. Gu, P. J. Ma, N. Gan, X. L. Wang, X. F. Long, and F. P. Zhang, Analyst, 2002, 127, 1657.
F. P. Zhang, S. P. Bi, F. Liu, and N. S. Bian, Anal. Lett., 2000, 33, 209.
F. P. Zhang, S. P. Bi, J. Liu, X. D. Yang, X. L. Wang, L. Yang, T. Yu, Y. J. Chen, L. M. Dai, and T. M. Yang, Anal. Sci., 2002, 18, 293.
F. P. Zhang, L. Yang, S. P. Bi, J. Liu, F. Liu, X. L. Wang, X. D. Yang, N. Gan, T. Yu, J. Hu, H. Z. Li, and T. M. Yang, J. Inorg. Biochem., 2001, 87, 105.
F. P. Zhang, S. P. Bi, H. Z. Li, Y. J. Chen, and L. M. Dai, Electroanalysis, 2001, 13, 1054.
F. P. Zhang, S. P. Bi, J. R. Zhang, N. S. Bian, F. Liu, and Y. Q. Yang, Analyst, 2000, 125, 1299.
J. Mauzeroll, M. Buda, A. J. Bard, F. Prieto, and M. Rueda, Langmuir, 2002, 18, 9453.
S. P. Bi, B. Liu, F.-R. F. Fan, and A. J. Bard, J. Am. Chem. Soc., 2005, 127, 3690.
R. M. Wightman, Science, 2006, 311, 1570.
M. Pessiglione, B. Seymour, G. Flandin, R. J. Dolan, and C. D. Frith, Nature, 2006, 442, 1042.
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Zhang, F., Zhang, M., Cheng, J. et al. Direct Voltammetric Specific Recognition of Dopamine Using AlIII-DA Complexes at the Hanging Mercury Drop Electrode. ANAL. SCI. 23, 1325–1329 (2007). https://doi.org/10.2116/analsci.23.1325
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DOI: https://doi.org/10.2116/analsci.23.1325