Anti-Microbial Susceptibility Pattern of Fosfomycin in Various Clinical Isolates
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Abstract
To identify the susceptibility pattern of Fosfomycin in various clinical isolates by estimating the frequency in terms of percentages. A convenient sampling technique was adopted for study proceedings. Total 748(n) specimens for culture and sensitivity were received in the microbiology section of pathology department. Out of these 748(n) specimens, positive cultures were seen in 144(n). For culture and sensitivity proceedings, the recommended CLSI – 2014 (clinical and laboratory standard institute) guidelines were followed. The bacterial isolation was done by biochemical tests. The zone diameter of >16 mm for 50µgm fosfomycin disc was considered as sensitive zone. While <15-12mm was considered as intermittent one and <12mm was the resistant zone. Data was recorded and analyzed by using SPSS version 20 for statistical inference. For numerical variables frequencies were calculated in terms of percentages. Seventy six 76.06% (n=143) gram negative and 68.42 % (n=13) gram positive organisms were sensitive to Fosfomycin. The efficacy of fosfomycin is more for gram negative (76%) as compared to gram positive organisms (68%).