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HomeInternational Letters of Chemistry, Physics and...International Letters of Chemistry, Physics and...Hybrid Approach for Synthesis and Antimicrobial...

Hybrid Approach for Synthesis and Antimicrobial Activity of Heterocyclic Compounds

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Abstract:

We have synthesized novel series of N-(1-(2-(1-phenyl-3-(p-tolyl)-1H-pyrazol-4-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)ethylidene)arylaniline and their derivatives. The structures of synthesized compounds were well characterized by spectroscopic techniques. Antimicrobial activity of the newly synthesized derivatives was evaluated against gram positive (S. aureus and S. pyogenes), gram negative bacteria (E. coli and P. aeruginosa), and strains of fungi (C. albicans, A. niger and A. clavatus). Among the screened derivatives 5c, 5f, 5i, 5l and 5t demonstrated superior antimicrobial activity against microbial strains.

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Periodical:

International Letters of Chemistry, Physics and Astronomy (Volume 77)

Pages:

35-52

DOI:

https://doi.org/10.56431/p-2746bu

Citation:

Cite this paper

Online since:

January 2018

Authors:

Nisheeth C. Desai*, Darshita V. Vaja

Keywords:

Anti Fungal, Antibacterial, Microbial Strains, Spectroscopic Techniques

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Creative Commons CC BY 4.0

* - Corresponding Author

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