Voltammetric Determination of Sulfaclozine Sodium at Sephadex-modified Carbon Paste Electrode
DOI:
https://doi.org/10.17344/acsi.2019.5686Keywords:
Sulfaclozine Sodium, square wave voltammetry, sephadex carbon past electrode.Abstract
The electrochemical behavior of Sulfaclozine Sodium (SLC) was studied at a bare and sephadex-modified carbon paste electrodes by cyclic voltammetry and square wave voltammetry. The cyclic voltammetry (CV) showed a well-defined irreversible oxidation peak at 0.94 V in Britton- Robinson buffer pH 7.0. The strong affinity of SLC to sephadex allowed accumulation of SLC at the surface of electrode and thus higher electrochemical sensitivity to SLC. The influence of sephadex loading, the pH of the solution and the scan rate on the peak current was studied. A linear calibration curve covering the concentration range from 0.005 to 1 mM was obtained using SWV. The method was successfully applied for the determination of SLC in the veterinary pharmaceutical formulations with satisfactory accuracy and precision.
Downloads
Published
Issue
Section
License
Except where otherwise noted, articles in this journal are published under the Creative Commons Attribution 4.0 International LicenseĀ