Czech J. Food Sci., 2021, 39(3):176-180 | DOI: 10.17221/273/2020-CJFS

Appraisal of antioxidant potential and biological studies of bogan bail (Bougainvillea glabra) leaf extracts using different solventsOriginal Paper

Muhammad Riaz1, Humaira Fatima1, Muhammad Misbah ur Rehman2, Rahman Qadir ORCID...*,1, Shabbir Hussain*,3, Abdul Hafeez1, Abu Bakar Siddique1
1 Institute of Chemistry, Faculty of Sciences, University of Sargodha, Sargodha, Pakistan
2 Department of Chemistry, Faculty of Sciences, University of Lahore, Sargodha, Pakistan
3 Department of Chemistry, Faculty of Basic Sciences, Lahore Garrison University, Lahore, Pakistan

Current research work was performed to evaluate the antioxidant, antidiabetic, thrombolytic, and cytotoxic potential of Bougainvillea glabra leaf extracts with different solvents. Extraction of leaves was carried out by maceration using solvents of various polarity such as n-hexane, chloroform, ethyl acetate, n-butanol, and methanol. The highest values of total phenolic and flavonoid contents were assessed in methanolic extract, such as 58.57% and 29.41%, respectively. Antioxidant potential was measured by DPPH free radical, showing 65.16% scavenging activity in methanolic extract. Similarly, the reducing power of methanolic extract was also measured. Hemolytic activity of B. glabra leaf extracts was evaluated, and maximum percentage lysis was found as 6.86% in chloroform extract. The thrombolytic activity of B. glabra leaf extracts was evaluated against human red blood cells, and the maximum percentage of clot lysis was 59.10% in chloroform extract. Maximum antidiabetic activity (16.20%) was observed in methanolic extract. Overall, the presented results reveal that bogan bail extract is capable of being employed in nutra-pharmaceutical industry.

Keywords: B. glabra; scavenging; thrombolytic; antidiabetic; hemolytic

Published: June 29, 2021  Show citation

ACS AIP APA ASA Harvard Chicago IEEE ISO690 MLA NLM Turabian Vancouver
Riaz M, Fatima H, Misbah ur Rehman M, Qadir R, Hussain S, Hafeez A, Siddique AB. Appraisal of antioxidant potential and biological studies of bogan bail (Bougainvillea glabra) leaf extracts using different solvents. Czech J. Food Sci.. 2021;39(3):176-180. doi: 10.17221/273/2020-CJFS.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Akhtar M.T., Qadir R., Bukhari I., Ashraf R.A., Malik Z., Zahoor S., Murtaza M.A., Siddique F., Shah S.N.H., Saadia M. (2020): Antidiabetic potential of Nigella sativa L seed oil in alloxaninduced diabetic rabbits. Tropical Journal of Pharmaceutical Research, 19: 283-289. Go to original source...
    2. Ali M.S., Faruq K.O., Islam A., Nurullah A., Chowdhury K.A.A., Sayeed M.A. (2015): Thrombolytic and cytotoxic activities of Terminalia bellerica Roxb. Bangladesh Journal of Pharmacology, 16: 131-135. Go to original source...
    3. Carlson C., Hussain S.M., Schrand A.M., Braydich-Stolle L.K., Hess K.L., Jones R.L., Schlager J.J. (2008): Unique cellular interaction of silver nanoparticles: Size-dependent generation of reactive oxygen species. The Journal of Physical Chemistry, 112: 13608-13619. Go to original source... Go to PubMed...
    4. Chaovanalikit A., Wrolstad R. (2004): Total anthocyanins and total phenolics of fresh and processed cherries and their antioxidant properties. Journal of Food Science, 69: 67-72. Go to original source...
    5. Devasagayam T., Sainis K. (2002): Immune system and antioxidants, especially those derived from Indian medicinal plants. Indian Journal of Experimental Biology, 40: 639-655.
    6. Dewanto V., Wu X., Adom K.K., Liu R.H. (2002): Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. Journal of Agriculture and Food Chemistry, 50: 3010-3014. Go to original source... Go to PubMed...
    7. Iqbal S., Bhanger M.I., Anwar F. (2005): Antioxidant properties and component of some commercially available varieties of rice bran in Pakistan. Food Chemistry, 93: 265-272. Go to original source...
    8. Kumar H.K., Navyashree S., Rakshitha H., Chauhan J.B. (2012): Studies on the free radical scavenging activity of Syagrus romanzoffiana. International Journal of Pharmacy, 3: 81-84.
    9. Nostro A., Germano M., Dangelo V., Marino A., Cannatelli M. (2000). Extraction methods and bioautography for evaluation of medicinal plant antimicrobial activity. Letters in Applied Microbiology, 30: 379-384. Go to original source... Go to PubMed...
    10. Powell W., Catranis C., Maynard C. (2000): Design of self-processing antimicrobial peptides for plant protection. Letters in Applied Microbiology, 31: 163-168. Go to original source... Go to PubMed...
    11. Prasad S., Kashyap R.S., Deopujari J.Y., Purohit H.J., Taori G.M., Daginawala H.F. (2007): Effect of Fagonia arabica (Dhamasa) on in vitro thrombolysis. BMC Complementary Medicine and Therapy, 7: 1-6. Go to original source... Go to PubMed...
    12. Qadir R., Anwar F., Gilani M.A., Zahoor S., Misbah ur Rehman M., Mustaqeem M. (2019): RSM/ANN based optimized recovery of phenolics from mulberry leaves by enzyme-assisted extraction. Czech Journal of Food Sciences., 37: 99-105. Go to original source...
    13. Qadir R., Anwar F., Mehmood T., Zahoor S., Mehmood N. (2020): Variations in biological attributes and phenolics of enzymatically hydrolysed medicinal plant extracts. Bangladesh Journal of Botany, 49: 163-169. Go to original source...
    14. Riaz M., Rasool N., Bukhari I.H., Shahid M., Zubair M., Rizwan K., Rashid U. (2012): In vitro antimicrobial, antioxidant, cytotoxicity and GC-MS analysis of Mazus goodenifolius. Molecules, 17: 14275-14287. Go to original source... Go to PubMed...
    15. Rizwan K., Zubair M., Rasool N., Riaz M., Zia-Ul-Haq M., Feo D.V. (2012): Phytochemical and biological studies of Agave attenuata. International Journal of Molecular Science, 13: 6440-6451. Go to original source... Go to PubMed...
    16. Samad A., Sultana Y., Aqi M. (2007): Liposomal drug delivery systems: An update review. Current Drug Delivery, 4: 297-305. Go to original source... Go to PubMed...
    17. Siddhuraju P., Becker K. (2003): Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. Journal of Agricultural and Food Chemistry, 51: 2144-2155. Go to original source... Go to PubMed...
    18. Yen G.C., Duh P.D., Chuang D.Y. (2000): Antioxidant activity of anthraquinones and anthrone. Food Chemistry, 70: 437-441. Go to original source...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content