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Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning

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Abstract

Objective

To report clinical features and treatment of 16 cases of acute 2,4-dinitrophenol poisoning.

Methods

A total of 16 patients suffering from acute poisoning due to non-oral exposure to 2,4-dinitrophenol were sent to our hospital. Two died within 3 h after admission, while the other 14 responded to supportive treatment and hemoperfusion. Clinical features and treatment of the patients were retrospectively analyzed and presented.

Results

Fourteen patients recovered and were discharged after four to six weeks of treatment. No obvious poisoning sequelae were found in the three-month follow-up.

Conclusions

Non-oral exposure to 2,4-dinitrophenol is toxic. Hemoperfusion and glucocorticoid treatments may be efficient measures to prevent mortality, but this requires further study.

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Correspondence to Wei-dong Huang.

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Lu, Yq., Jiang, Jk. & Huang, Wd. Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning. J. Zhejiang Univ. Sci. B 12, 189–192 (2011). https://doi.org/10.1631/jzus.B1000265

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  • DOI: https://doi.org/10.1631/jzus.B1000265

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