1992 Volume 168 Issue 2 Pages 83-87
POLAND, A, and BRADFIELD, C. A Brief Review of the Ah Locus. Tohoku J. Exp. Med., 1992, 168 (2), 83-87 - The Ah locus, first described as a functional polymorphism among inbred strains of mice, encodes the Ah receptor-a ligand dependent transcriptional activator. This paper reviews the work on the Ah receptor and its importance in the expression of cytochrome P-450IA1 and the pleiotropic effects of halogenated aromatic hydrocarbons. - Ah locus; Ah receptor; cytochrome P-450IA1; halogeneted aromatic hydrocarbons