Biópsia estereotáxica para linfomas primários do sistema nervoso central

Meneses, Murilo S.; O'Neill, Brian P.; Kelly, Patrick J.

doi:10.1590/S0004-282X1992000300010

Resumos

Os linfomas primários do SNC são raros, mas sua incidência tem aumentado nos últimos anos, Estes tumores frequentemente se localizam nos gânglios da base e tálamo ou se apresentam de forma multifocal. O tratamento atual para eles é a radioterapia, associada ou não a quimioterapia. Devido à sua extremamente baixa morbidade, a biópsia estereo-táxica é o método ideal para determinar o diagnóstico histológico em pacientes com suspeita de linfomas do SNC. Os autores apresentam estudo de 49 casos de linfomas primários do SNC, diagnosticado por biópsia estereotáxica.

linfomas do SNC; biópsia; estereotaxia; tumores intracranianos

Primary lymphomas of the CNS are rare. However the incidence of these lesions has increased recently. These tumors are often situated in the thalamus and basal ganglia, but can be multifocal. The treatment for primary CNS lymphoma is radiotherapy alone or in association with chemotherapy. Because the associated morbidity is very low stereotactic biopsy is an ideal method for determining the histologic diagnosis in patients with suspected CNS lymphoma. The authors present a study of 49 patients with primary CNS lymphomas in which a stereotactic biopsy was performed.

CNS lymphomas; biopsy; stereotaxy; intracranial tumors

Murilo S. Meneses; Brian P. O'Neill; Patrick J. Kelly

Departments of Neurological Surgery and Neurology, Mayo Clinic, Rochester, Minnesota, USA. Dr. Murilo S. Meneses é também Neurocirurgião do Hospital das Nações (Curitiba) e Professor de Neuroanatomia da Universidade Federal do Paraná

RESUMO

Os linfomas primários do SNC são raros, mas sua incidência tem aumentado nos últimos anos, Estes tumores frequentemente se localizam nos gânglios da base e tálamo ou se apresentam de forma multifocal. O tratamento atual para eles é a radioterapia, associada ou não a quimioterapia. Devido à sua extremamente baixa morbidade, a biópsia estereo-táxica é o método ideal para determinar o diagnóstico histológico em pacientes com suspeita de linfomas do SNC. Os autores apresentam estudo de 49 casos de linfomas primários do SNC, diagnosticado por biópsia estereotáxica.

Palavras-chave: linfomas do SNC, biópsia, estereotaxia, tumores intracranianos.

SUMMARY

Primary lymphomas of the CNS are rare. However the incidence of these lesions has increased recently. These tumors are often situated in the thalamus and basal ganglia, but can be multifocal. The treatment for primary CNS lymphoma is radiotherapy alone or in association with chemotherapy. Because the associated morbidity is very low stereotactic biopsy is an ideal method for determining the histologic diagnosis in patients with suspected CNS lymphoma. The authors present a study of 49 patients with primary CNS lymphomas in which a stereotactic biopsy was performed.

Key words: CNS lymphomas, biopsy, stereotaxy, intracranial tumors.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Dr. Murilo S. Meneses - Avenida Getulio Vargas 2159 - 80230 Curitiba PR - Brasil.

1. Apuzzo MJL, Chandrasoma FT, Cohen D, Zee CS, Zelman, V. Computed imaging stereotaxy: experience and perspective related to 500 procedures applied to brain masses. Neurosurgery 1987, 20:930-937.
2. Ashby MA, Bowen D, Bleehen NM, Barber PC, Freer CE. Primary lymphoma of the central nervous system at Addenbrooke's Hospital, Cambridge. Clin Radiol 1988, 39:173-181.
3. Berry MP, Simpson WJ. Radiation therapy in the management of primary malignant lymphoma of the brain. Int J Radiat Oncol Biol Phys 1981, 7:56-59.
4. Bogdahn U, Bogdahn S, Mertens HG, Dommasch D, Wodarz R. Wunsch PH, Kuhl P, Richter E. Primary non-Hodgkin's lymphoma of the CNS. Acta Neurol Scand 1986, 73:602-614.
5. Davis DH, Kelly PJ, Marsch WR, Kall BA, Goerss SJ. Computer-assisted stereotactic biopsy of intracranial lesions. Appl Neurophisiol 1987, 50:172-177.
6. Feiden W, Bise K, Steude U. Diagnosis of primary cerebral lymphoma with particular reference to CT-guided stereotactic biopsy. Virchows Archiv R Pathol Anat. 1990, 417 : 21-28.
7. Formenti SC, Gill PS, Lean E, Rarick M, Meyer PR, Boswell W, Petrovich Z, Chak L, Devine AM. Primary central nervous lymphoma in AIDS: results of radiation therapy. Cancer 1989, 63:1101-1107.
8. Freeman C, Bery JW, Cutler SJ. Occurence and prognosis of extranodal lymphomas. Cancer 1972, 29:252-260.
9. Gonzalez D, Schuster-Uitterhoeve ALJ. Primary non Hodgkin's lymphomas of the central nervous system: results of radiotherapy in 15 cases. Cancer 1983, 51 :2048-2052.
10. Hochberg FH, Miller DC. Primary central nervous system lymphoma. J Neurosurg 1988, 68 : 835-853.
11. Homo-Delarche F. Glucocorticoid receptors and steroid sensitivity in normal and neoplastic human lymphoid tissues: a review. Cancer Res 1984, 44:431-437.
12. Kawakami Y, Tabuchi K, Ohnishi R, Asari S, Nishimoto A. Primary sistem lymphoma. J Neurosurg 1985, 62:522-527.
13. Kelly PJ Stereotactic biopsy and resection of thalamic astrocytomas. Neurosurgery 1989, 25:185-195.
14. Kelly PJ, Earnest F, Kall BA, Goerss SJ, Scheithauer B. Surgical options for patients with deepseated brain tumors: computer-assisted stereotactic biopsy. Mayo Clinic Proc 1985, 60:223-229.
15. Kelly PJ, Kall BA. Goerss SJ, Earnest F. Computer-assisted stereotaxic laser resection of intra-axial brain neoplasms. J Neurosurg 1989, 64:427-439.
16. Kotasek D, Albertyn DE, Sage RE. A five year experience with central nervous system lymphoma. Med J Aust 1986, 144 : 229-303.
17. Letendre L, Banks PM, Reese DF, Miller RH, Scanlon PW, Kiely JM. Primary lymphoma of the central nervous system. Cancer 1982, 49:939-943.
18. Littman P, Wang CC. Reticulum cell sarcoma of the brain. Cancer 1975, 35:1412-1420.
19. Loeffler JS, Ervin TJ, Mauch P, Skarin A, Weinstein HJ, Canellos G, Cassady JR. Primary lymphomas of the central nervous system: patterns of failure and factors that influence survival. J Clin Oncol 1985, 3:490-494.
20. Lunsford DD. Diagnosis and treatment of mass lesions using the Leksell stereotactic system, In: Dunsford LD (ed) : Modern Stereotactic Neurosurgery. Boston: Nijhof, 1988, p 145-168.
21. McKinstry CS Intracranial malignant lymphoma. J Neurosurg 1987, 67:476-477.
22. Meneses MS, Kelly PJ. Microcirurgia estereotáxica para remoção radical de cistos colóides do terceiro ventrículo. Arq Bras Neurocir (no prelo).
23. Meneses MS, Thurel C, Mikol J, Ramina R, Maniglia JJ, Arruda WO, Cophignon J. Esthesioneuroblastoma with intracranial extension. Neurosurgery 1990, 27:813-820.
24. Michalski JM, Garcia DM, Kase E, Erigsby PW, Simpson JR. Primary central nervous system lymphoma: analysis of prognostic variables and patterns of treatment failure. Radiology 1990, 179:855-860.
25. Murray K, Kun L, Cox J. Primary malignant lymphoma of the central nervous system: results of treatment of 11 cases and review of the literature. J Neurosurg 1986, 65:600-607.
26. Neuwelt EA, Frenkel EP, Gumerlock MK. Developments in the diagnosis and treatment of primary CNS lymphoma: a prospective series. Cancer 1986, 58:1609-1620.
27. Penn I. Lymphomas complicating organ transplantation. Transplant Proc 1983, 15:2790-2797.
28. Pollack IF, Lunsford LD, Flickinger JC, Dameshek HL. Prognostic factors in the diagnosis and treatment of primary central nervous lymphoma. Cancer 1989, 63:939-947.
29. Sherman ME, Erozan YS, Mann RB. Stereotactic brain biopsy in the diagnosis of malignan lymphoma. Ann J Clin Pathol 1991, 95:878-883.
30. So IT, Beckstead JH, Davis RL. Primary central nervous system lymphoma in acquired immune deficiency syndrom: a clinical and pathological study. Ann Neurol 1986, 20:566-572.
31. Woodmann R, Shin K, Pineo G. Primary non-Hodgkin's lymphoma of the brain. Medicine 1985, 64:425-430.
32w Ymasaki T, Kikuchi H, Yamashita J, Moritake K, Shibamoto Y, Paine JT, Shima M, Yamabe H. Intracerebral malignant lymphoma with fluctuating regression and spatial evolution. Surg Neurobiol 1990, 34:235-244.

Biópsia estereotáxica para linfomas primários do sistema nervoso central

Stereotactic biopsy for primary lymphomas of the central nervous system

Datas de Publicação

Publicação nesta coleção
22 Fev 2011
Data do Fascículo
Set 1992

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Apuzzo MJL, Chandrasoma FT, Cohen D, Zee CS, Zelman, V. Computed imaging stereotaxy: experience and perspective related to 500 procedures applied to brain masses. Neurosurgery 1987, 20:930-937.

[2] 2. Ashby MA, Bowen D, Bleehen NM, Barber PC, Freer CE. Primary lymphoma of the central nervous system at Addenbrooke's Hospital, Cambridge. Clin Radiol 1988, 39:173-181.

[3] 3. Berry MP, Simpson WJ. Radiation therapy in the management of primary malignant lymphoma of the brain. Int J Radiat Oncol Biol Phys 1981, 7:56-59.

[4] 4. Bogdahn U, Bogdahn S, Mertens HG, Dommasch D, Wodarz R. Wunsch PH, Kuhl P, Richter E. Primary non-Hodgkin's lymphoma of the CNS. Acta Neurol Scand 1986, 73:602-614.

[5] 5. Davis DH, Kelly PJ, Marsch WR, Kall BA, Goerss SJ. Computer-assisted stereotactic biopsy of intracranial lesions. Appl Neurophisiol 1987, 50:172-177.

[6] 6. Feiden W, Bise K, Steude U. Diagnosis of primary cerebral lymphoma with particular reference to CT-guided stereotactic biopsy. Virchows Archiv R Pathol Anat. 1990, 417 : 21-28.

[7] 7. Formenti SC, Gill PS, Lean E, Rarick M, Meyer PR, Boswell W, Petrovich Z, Chak L, Devine AM. Primary central nervous lymphoma in AIDS: results of radiation therapy. Cancer 1989, 63:1101-1107.

[8] 8. Freeman C, Bery JW, Cutler SJ. Occurence and prognosis of extranodal lymphomas. Cancer 1972, 29:252-260.

[9] 9. Gonzalez D, Schuster-Uitterhoeve ALJ. Primary non Hodgkin's lymphomas of the central nervous system: results of radiotherapy in 15 cases. Cancer 1983, 51 :2048-2052.

[10] 10. Hochberg FH, Miller DC. Primary central nervous system lymphoma. J Neurosurg 1988, 68 : 835-853.

[11] 11. Homo-Delarche F. Glucocorticoid receptors and steroid sensitivity in normal and neoplastic human lymphoid tissues: a review. Cancer Res 1984, 44:431-437.

[12] 12. Kawakami Y, Tabuchi K, Ohnishi R, Asari S, Nishimoto A. Primary sistem lymphoma. J Neurosurg 1985, 62:522-527.

[13] 13. Kelly PJ Stereotactic biopsy and resection of thalamic astrocytomas. Neurosurgery 1989, 25:185-195.

[14] 14. Kelly PJ, Earnest F, Kall BA, Goerss SJ, Scheithauer B. Surgical options for patients with deepseated brain tumors: computer-assisted stereotactic biopsy. Mayo Clinic Proc 1985, 60:223-229.

[15] 15. Kelly PJ, Kall BA. Goerss SJ, Earnest F. Computer-assisted stereotaxic laser resection of intra-axial brain neoplasms. J Neurosurg 1989, 64:427-439.

[16] 16. Kotasek D, Albertyn DE, Sage RE. A five year experience with central nervous system lymphoma. Med J Aust 1986, 144 : 229-303.

[17] 17. Letendre L, Banks PM, Reese DF, Miller RH, Scanlon PW, Kiely JM. Primary lymphoma of the central nervous system. Cancer 1982, 49:939-943.

[18] 18. Littman P, Wang CC. Reticulum cell sarcoma of the brain. Cancer 1975, 35:1412-1420.

[19] 19. Loeffler JS, Ervin TJ, Mauch P, Skarin A, Weinstein HJ, Canellos G, Cassady JR. Primary lymphomas of the central nervous system: patterns of failure and factors that influence survival. J Clin Oncol 1985, 3:490-494.

[20] 20. Lunsford DD. Diagnosis and treatment of mass lesions using the Leksell stereotactic system, In: Dunsford LD (ed) : Modern Stereotactic Neurosurgery. Boston: Nijhof, 1988, p 145-168.

[21] 21. McKinstry CS Intracranial malignant lymphoma. J Neurosurg 1987, 67:476-477.

[22] 22. Meneses MS, Kelly PJ. Microcirurgia estereotáxica para remoção radical de cistos colóides do terceiro ventrículo. Arq Bras Neurocir (no prelo).

[23] 23. Meneses MS, Thurel C, Mikol J, Ramina R, Maniglia JJ, Arruda WO, Cophignon J. Esthesioneuroblastoma with intracranial extension. Neurosurgery 1990, 27:813-820.

[24] 24. Michalski JM, Garcia DM, Kase E, Erigsby PW, Simpson JR. Primary central nervous system lymphoma: analysis of prognostic variables and patterns of treatment failure. Radiology 1990, 179:855-860.

[25] 25. Murray K, Kun L, Cox J. Primary malignant lymphoma of the central nervous system: results of treatment of 11 cases and review of the literature. J Neurosurg 1986, 65:600-607.

[26] 26. Neuwelt EA, Frenkel EP, Gumerlock MK. Developments in the diagnosis and treatment of primary CNS lymphoma: a prospective series. Cancer 1986, 58:1609-1620.

[27] 27. Penn I. Lymphomas complicating organ transplantation. Transplant Proc 1983, 15:2790-2797.

[28] 28. Pollack IF, Lunsford LD, Flickinger JC, Dameshek HL. Prognostic factors in the diagnosis and treatment of primary central nervous lymphoma. Cancer 1989, 63:939-947.

[29] 29. Sherman ME, Erozan YS, Mann RB. Stereotactic brain biopsy in the diagnosis of malignan lymphoma. Ann J Clin Pathol 1991, 95:878-883.

[30] 30. So IT, Beckstead JH, Davis RL. Primary central nervous system lymphoma in acquired immune deficiency syndrom: a clinical and pathological study. Ann Neurol 1986, 20:566-572.

[31] 31. Woodmann R, Shin K, Pineo G. Primary non-Hodgkin's lymphoma of the brain. Medicine 1985, 64:425-430.

[32] 32w Ymasaki T, Kikuchi H, Yamashita J, Moritake K, Shibamoto Y, Paine JT, Shima M, Yamabe H. Intracerebral malignant lymphoma with fluctuating regression and spatial evolution. Surg Neurobiol 1990, 34:235-244.