Sterols and flavone from the leaves of Vernonia amygdalina growing in Thua Thien Hue

Hoang Le Tuan Anh; Le Thi  Lien; Pham Viet  Cuong; Masayoshi  Arai; Tran Phuong  Ha; Ton That Huu  Dat; Le Canh Viet  Cuong

doi:10.15625/2525-2518/56/6/12584

Author affiliations

Authors

Hoang Le Tuan Anh Mientrung Institute for Scientific Research, Vietnam Academy of Science and Technology (VAST), 321 Huynh Thuc Khang, Hue city, Thua Thien Hue, Viet Nam
Le Thi Lien Mientrung Institute for Scientific Research, Vietnam Academy of Science and Technology (VAST), 321 Huynh Thuc Khang, Hue city, Thua Thien Hue, Viet Nam
Pham Viet Cuong Mientrung Institute for Scientific Research, Vietnam Academy of Science and Technology (VAST), 321 Huynh Thuc Khang, Hue city, Thua Thien Hue, Viet Nam
Masayoshi Arai Research Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan
Tran Phuong Ha Mientrung Institute for Scientific Research, Vietnam Academy of Science and Technology (VAST), 321 Huynh Thuc Khang, Hue city, Thua Thien Hue, Viet Nam
Ton That Huu Dat Mientrung Institute for Scientific Research, Vietnam Academy of Science and Technology (VAST), 321 Huynh Thuc Khang, Hue city, Thua Thien Hue, Viet Nam
Le Canh Viet Cuong Mientrung Institute for Scientific Research, Vietnam Academy of Science and Technology (VAST), 321 Huynh Thuc Khang, Hue city, Thua Thien Hue, Viet Nam

DOI:

https://doi.org/10.15625/2525-2518/56/6/12584

Keywords:

Vernonia amygdalina, sterol, vernoniamygda A, vernoniamygda B, luteolin

Abstract

By using various chromatographic methods, two sterols and one flavone, vernoniamygda A (1), vernoniamygda B (2), and luteolin (3) were isolated from the methanol extract of the leaves of Vernonia amygdalina. Their structures were determined using 1D, 2D-NMR and ESI-MS analysis as well as by comparison with the reported data. Compounds 1 and 2 were reported from natural for the first time.

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