Abstract
Calcium phosphate based thin films prepared by colloidal sol-gel slow draw dipping of quartz substrates are bioactive to both osteoclast resorption and osteoblast deposition. The bioactivity is related to the presence of mixed crystalline phases in the films generated under different sintering conditions. As the sintering temperature was increased from 800°C to 1000°C, a transition in film composition from calcium hydroxylapatite to alpha-tricalcium phosphate is achieved.
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Acknowledgments
The authors gratefully acknowledges the Natural Science and Engineering Research Council for funding part of this research. Collaboration with Dr. J. E. Davies of the Centre for Biomaterials, University of Toronto is appreciated. Osteologic™ substrates have been provided by Millenium Biologix Inc.
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Langstaff, S., Sayer, M., Weaver, L. et al. Thin Film Phosphate Based Bioactive Substrates. MRS Online Proceedings Library 414, 87–92 (1995). https://doi.org/10.1557/PROC-414-87
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DOI: https://doi.org/10.1557/PROC-414-87