A Case of Atrial Septal Defect Combined with Hypertension and Left Ventricular Hypertrophy Left Ventricular Failure Induced by Balloon Occlusion and the Effect of Nifedipine

Taku MATSUBARA; Masaru YAMAZOE; Takashi KOIKE; Tohru IZUMI; Akira SHIBATA

doi:10.1536/ihj.30.103

A Case of Atrial Septal Defect Combined with Hypertension and Left Ventricular Hypertrophy

Left Ventricular Failure Induced by Balloon Occlusion and the Effect of Nifedipine

Taku MATSUBARA, Masaru YAMAZOE, Takashi KOIKE, Tohru IZUMI, Akira SHIBATA

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Keywords: Atrial septal defect, Left ventricular function, Balloon occlusion test, Nifedipine

JOURNAL FREE ACCESS

1989 Volume 30 Issue 1 Pages 103-107

DOI https://doi.org/10.1536/ihj.30.103

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Abstract

A 46 year old woman with hypertension and left ventricular hypertrophy accompanied by an atrial septal defect is reported. Hemodynamic changes induced by balloon occlusion and concomitant nifedipine were studied. Left ventricular failure appeared after balloon closure of the defect. Nifedipine decreased the increment in left ventricular enddiastolic pressure induced by balloon occlusion. After the reduction of systemic vascular resistance, the ratio of intracardiac shunt flow was still larger. Surgical closure of the defect was performed and the postoperative course was good with the use of vasodilators

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