Primary Thrombocythemia and Myocardial Infarction in a 26-Year-Old Woman with Normal Coronary Arteriogram

Noriko OKAYASU; Mizuho MURATA; Akira UEDA; Kan-Min SU; Toshikatsu SADA; Takashi ITO; Yoshiyasu HASEGAWA; Shinsaku MATSUMOTO; Yoshio ITO

doi:10.1536/ihj.22.439

Noriko OKAYASU, Mizuho MURATA, Akira UEDA, Kan-Min SU, Toshikatsu SADA, Takashi ITO, Yoshiyasu HASEGAWA, Shinsaku MATSUMOTO, Yoshio ITO

Author information

Noriko OKAYASU
Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Mizuho MURATA
Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Akira UEDA
Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Kan-Min SU
Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Toshikatsu SADA
Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Takashi ITO
Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Yoshiyasu HASEGAWA
Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Shinsaku MATSUMOTO
Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
Yoshio ITO
Sanraku Hospital

Keywords: Platelet aggregation, Stillbirth

JOURNAL FREE ACCESS

1981 Volume 22 Issue 3 Pages 439-445

DOI https://doi.org/10.1536/ihj.22.439

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Abstract

Acute myocardial infarction occurred in a 26-year-old woman with normal coronary arteriogram and primary thrombocythemia (500, 000-1, 500, 000/mm³).
Hyperaggregability of platelets was also demonstrated by stimulation with adenosine diphosphate, collagen, and epinephrine administration. A stillbirth at the 8th month of gestation in her past history was referred to the complication of primary thrombocythemia, too. Since discharge, the patient has been on 750mg of aspirin and then free of any thromboembolic symptoms and signs, even during pregnancy and labour.

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