5 - Modifying porous silicon with self-assembled monolayers for biomedical applications

https://doi.org/10.1533/9780857097156.1.81Get rights and content

Abstract:

Many biomedical applications of porous silicon (PSi) require the surface of the material to be modified such that it interfaces with the biological system in a controlled way. This is particularly true if PSi is to be used for biosensing. There have been a number of strategies for modifying PSi, including polymers, oxidation and a variety of different self-assembled monolayer systems. Herein is reviewed the modification strategies that employ self-assembled monolayers, including a discussion of their advantages and disadvantages. Monolayer strategies for modifying PSi fall typically into two categories. In the first category, PSi is oxidized and reacted with organosilanes. In the second category, hydrogen-terminated PSi surfaces are reacted with molecules that possess terminal alkenes and alkynes, which is referred to as a hydrosilylation reaction. Both methods are covered in detail in this chapter, along with strategies for introducing multiple chemical functionalities on the PSi surfaces.

References (0)

Cited by (5)

View full text