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Transient Increase of Serum Granulysin in a Stage IVs Neuroblastoma Patient during Spontaneous Regression: Case Report

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References

  1. Pritchard J, Hickman JA. Why does stage 4s neuroblastoma regress spontaneously? Lancet. 1994;344:869–870.

    Article  CAS  Google Scholar 

  2. Kitanaka C, Kato K, Ijiri R, et al. Increased Ras expression and caspase-independent neuroblastoma cell death: possible mechanism of spontaneous neuroblastoma regression. J Natl Cancer Inst. 2002;94:358–368.

    Article  CAS  Google Scholar 

  3. Gestblom C, Hoehner JC, Pahlman S. Proliferation and apoptosis in neuroblastoma: subdividing the mitosis-karyorrhexis index. Eur J Cancer. 1995;31:458–463.

    Article  Google Scholar 

  4. Kishi A, Takamori Y, Ogawa K, et al. Differential expression of granulysin and perforin by NK cells in cancer patients and correlation of impaired granulysin expression with progression of cancer. Cancer Immunol Immunother. 2002;50:604–614.

    Article  CAS  Google Scholar 

  5. Ogawa K, Takamori Y, Nagasawa M, et al. Granulysin in human serum as a marker of cell-mediated immunity. Eur J Immunol. 2003;33:1925–1933.

    Article  CAS  Google Scholar 

  6. Ochoa MT, Stenger S, Sieling PA, et al. T-cell release of granulysin contributes to host defense in leprosy. Nat Med. 2001;7:174–179.

    Article  CAS  Google Scholar 

  7. Stenger S, Hanson DA, Teitelbaum R, et al. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science. 1998;282:121–125.

    Article  CAS  Google Scholar 

  8. Dieli F, Troye-Blomberg M, Ivanyi J, et al. Granulysin-dependent killing of intracellular and extracellular Mycobacterium tuberculosis by Vγ9/Vδ2 T lymphocytes. J Infect Dis. 2001;184:1082–1085.

    Article  CAS  Google Scholar 

  9. Gamen S, Hanson DA, Kaspar A, Naval J, Krensky AM, Anel A. Granulysin-induced apoptosis, I: involvement of at least two distinct pathways. J Immunol. 1998;161:1758–1764.

    PubMed  CAS  Google Scholar 

  10. Matthay KK, Perez C, Seeger RC, et al. Successful treatment of stage III neuroblastoma based on prospective biologic staging: a Children’s Cancer Group study. J Clin Oncol. 1998;16:1256–1264.

    Article  CAS  Google Scholar 

  11. Chicheportiche Y, Bourdon PR, Xu H, et al. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J Biol Chem. 1997;272:32401–32410.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics and Developmental Biology, Graduate School, Tokyo Medical and Dental University, 5-45, Yushima 1-chome, Bunkyo-ku, 113-8519, Tokyo, Japan

    Masayuki Nagasawa, Hiroshi Kawamoto, Yoichirou Tsuji & Shuki Mizutani

Authors
  1. Masayuki Nagasawa
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  2. Hiroshi Kawamoto
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  3. Yoichirou Tsuji
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  4. Shuki Mizutani
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Correspondence to Masayuki Nagasawa.

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Nagasawa, M., Kawamoto, H., Tsuji, Y. et al. Transient Increase of Serum Granulysin in a Stage IVs Neuroblastoma Patient during Spontaneous Regression: Case Report. Int J Hematol 82, 456–457 (2005). https://doi.org/10.1532/IJH97.05091

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  • DOI: https://doi.org/10.1532/IJH97.05091

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