Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
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Recommendation of Occupational Exposure Limit through occupational hazard assessment of PHMG-Phosphate

PHMG-Phosphate의 직업적 유해성평가를 통한 노출기준 제안 연구

  • Lee, Hye Lim (Department of Environmental Health, College of Health Science, Korea University) ;
  • Byeon, Sang Hoon (Department of Environmental Health, College of Health Science, Korea University) ;
  • Lee, Kwon Seob (Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency)
  • 이혜림 (고려대학교 보건과학대학) ;
  • 변상훈 (고려대학교 보건과학대학) ;
  • 이권섭 (한국산업안전보건공단 산업안전보건연구원)
  • Received : 2018.12.13
  • Accepted : 2019.03.08
  • Published : 2019.03.31
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Abstract

Objective: This study was performed to propose a domestic occupational exposure limit(OEL) following a health hazard assessment, calculation of a non-carcinogenicity reference concentration worker($RfC_{worker}$) value, and examination of international agencies' exposure limits. It also recommends legal management within the Occupational Safety and Health Act for PHMG-Phosphate(CAS No. 89697-78-9), It is a humidifier disinfectant that generated many lung injuries. Methods: We have investigated the recommendation or guidelines of foreign OEL for PHMG-Phosphate and the actual state of legal management in Korea. To examine the procedures and methods for recommendation OEL. Toxicological hazard and health hazard classifications were examined and a non-carcinogenicity $RfC_{worker}$ value was calculated for PHMG-Phosphate. An OEL and the necessity of legal management were recommended as well. Results and Conclusions: The OEL for PHMG-Phosphate is recommended to be $0.01mg/m^3$. The recommended OEL is close to 10 times the RfCworker value of $0.000833mg/m^3$ calculated from the chemical dose-response hazard assessment, which is a 2017 study. The CMIT/MIT(3:1) mixture, which was a social issue as a humidifier disinfectant substance, was also exposed to the same ratio in March 2018, establish the OEL. It is recommended to establish OEL for PHMG-Phosphate to prevent worker health hazards and for chemical safety management.

Keywords

Table 1. The Results of the survey on the establishment of Occupational exposure limits and the actual state of legal management for PHMG-Phosphate

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Table 2. Results of toxicological hazard assessment for PHMG-Phosphate in NIER(summary of toxic material properties and toxicity and management information)

SOOSB1_2019_v29n1_13_t0002.png 이미지

Table 3. The comparison of classification results of the GHS health hazard for PHMG-Phosphate

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Table 4. The calculation of RfCworker Value for PHMG-Phosphate

SOOSB1_2019_v29n1_13_t0004.png 이미지

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