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Towards the pharmacogenomics of cystic fibrosis

    Federica Sangiuolo

    Dipartimento di Biopatologia e Diagnostica per Immagini, Università di Roma Tor Vergata and Servizio di Genetica Medica Policlinico Universitario Tor Vergata, 00133 Roma, Italy

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    ,
    Maria Rosaria D’Apice

    Dipartimento di Biopatologia e Diagnostica per Immagini, Università di Roma Tor Vergata and Servizio di Genetica Medica Policlinico Universitario Tor Vergata, 00133 Roma, Italy

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    ,
    Emanuela Bruscia

    Dipartimento di Biopatologia e Diagnostica per Immagini, Università di Roma Tor Vergata and Servizio di Genetica Medica Policlinico Universitario Tor Vergata, 00133 Roma, Italy

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    ,
    Vincenzina Lucidi

    Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy

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    ,
    Giuseppe Novelli

    Dipartimento di Biopatologia e Diagnostica per Immagini, Università di Roma Tor Vergata and Servizio di Genetica Medica Policlinico Universitario Tor Vergata, 00133 Roma, Italy

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    Published Online:4 Nov 2004https://doi.org/10.1517/14622416.3.1.75

    Abstract

    Keywords: cystic fibrosis, cystic fibrosis transmembrane conductance regulator, CFTR mutations, gene therapy, genotype-phenotype correlation, ion channel therapy, pharmacological treatment, protein-assisted therapy